Deans' stroke musings: Association between stroke and memory diseases: evidence from a prospective national cohort study in China

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, June 20, 2025

Association between stroke and memory diseases: evidence from a prospective national cohort study in China

Why can't your stroke medical 'professionals' deliver recovery instead of this useless association crapola? Are they that fucking incompetent?

Association between stroke and memory diseases: evidence from a prospective national cohort study in China

Kai Zhou, Jiehua Gan, Guomin Xie, Xiao Chen and Zhongyue Lv*

Department of Neurology, Ningbo Medical Center Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China

Edited by

Amin Gasmi, Francophone Society of Nutritherapy and Applied Nutrigenetics, France

Reviewed by

Weimin Yang, First Affiliated Hospital of Zhengzhou University, China

Jing Shang, The First Affiliated Hospital of Soochow University, China

*Correspondence

Zhongyue Lv, lzy_neuro@163.com

Received 10 March 2025

Accepted 02 June 2025

Published 19 June 2025

Citation

Zhou K, Gan J, Xie G, Chen X and Lv Z (2025) Association between stroke and memory diseases: evidence from a prospective national cohort study in China. Front. Neurol. 16:1578200. doi: 10.3389/fneur.2025.1578200

Background:

Previous studies had shown stroke played an important role in the pathogenesis of memory diseases. Thus, this study investigated the correlation between stroke and memory diseases [Alzheimer’s disease (AD) and brain atrophy] and provided a new theoretical basis for the diagnosis of stroke disease.

Methods:

A total of 15,904 total participants were obtained based on the China Health and Retirement Longitudinal Study (CHARLS), including 322 stroke subjects and 15,582 control subjects. Stroke was outcome variable, after the questionnaire, the subjects were divided into stroke and control groups. Meanwhile, various categorical variables, such as memory diseases (AD, brain atrophy), gender and medical insurance were included in this study. The weighted chi-square test was used to analyze whether there were differences in covariates between stroke and control groups. In addition, the correlation between memory diseases and stroke were analyzed by weighted logistic regression. Receiver operating characteristic (ROCs) curves were used to assess the accuracy and reliability of the Model III.

Results:

Stroke and control subjects differed significantly in a variety of clinical characteristics, and variables such as healthy status, patient service and memory diseases were significantly correlated with stroke prevalence. According to the three models constructed in this study, memory diseases was significantly associated with stroke in all three models (Model I, odds ratio (OR) = 7.33, p < 0.001, 95% Confidence interval (CI) = 5.31–9.94; Model II, OR = 7.33, p < 0.001, 95% CI = 5.31–9.95; Model III, OR = 3.84, p < 0.001, 95% CI = 2.73–5.30). Weighted logistic regression analysis showed the stability of the relationship between memory diseases and stroke, further suggested the correlation between memory diseases and stroke. Finally, the area under curve (AUC) of 0.778 indicated that the prediction accuracy of Model III was better.

Conclusion: According to the results in this study, there was a significant association between memory diseases and stroke. It is worthwhile to further study the mechanisms between stroke and memory diseases.