Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, September 30, 2025

Vagus nerve and brain–gut communication in neurodegenerative diseases: mechanism and therapeutic perspectives

 You competent? doctor created EXACT PROTOCOLS on vagus nerve stimulation and the gut-brain axis a decade ago, right? Oh no, you have a fucking INCOMPETENT DOCTOR THAT DID NOTHING, RIGHT!

All this earlier research on vagus nerve stimulation and you still haven't written a protocol on it and distributed it worldwide.

And let's see how long your doctor has been incompetent on the gut-brain axis, only 9 years!

  • Dietary Index for Gut Microbiota (1 post to May 2025)

  • gut-brain axis (38 posts to June 2016)

  • gut microbiota (33 posts to June 2016)
  • gut microbiota dysbiosis (2 posts to March 2022)
  • gut microbiota transplants (1 post to October 2023) You need to be aware of this problem. 
  • The latest here:

    • I'd fire you all for incompetence!

    Vagus nerve and brain–gut communication in neurodegenerative diseases: mechanism and therapeutic perspectives


    https://doi.org/10.1016/j.phrs.2025.107974Get rights and content
    Under a Creative Commons license
    Open access

    Abstract

    Neurodegenerative diseases (NDs) are characterized by degenerative nerve damage, and available therapeutic drugs cannot prevent or slow down their progression. The pathogenesis of NDs is related to the brain–gut axis, but the regulatory mechanisms are not yet fully understood. The vagus nerve, the main neural pathway of the brain–gut axis, plays a crucial role in the occurrence and development of NDs. This study summarizes the molecular mechanisms by which the vagus nerve regulates intestinal immunity and neuroinflammatory homeostasis of NDs to improve movement disorders and mental disorders. Intestinal immune dysregulation promotes the transfer of metabolites through the vagus nerve to the brain, leading to a general imbalance between the central immune response and the peripheral immune response and enhancing the level of systemic inflammatory stress. Intestinal immune responses and metabolic imbalances cause brain immune imbalances mediated by the vagus nerve and brain–gut communication. Targeted strategies of vagus nerve and brain–gut communication, including intelligent engineered strains systems, genetic-engineering strain modification, artificial intelligence dynamic monitoring, vagus nerve stimulation, polysaccharides, and natural small molecules, can help improve the symptoms of NDs. This study emphasizes that vagus nerve and brain–gut communication can serve as novel targets for NDs.
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