Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, September 18, 2025

Pathogenic Mechanisms of Cerebral Ischemia and Potential Gut-Brain Axis-Oriented Therapeutic Strategies

 Let's see how long your doctor and hospital have been incompetent in not creating gut-brain protocols. WOW! Almost a decade and the incompetent board of directors hasn't fired everybody in the hospital for extreme incompetence?

  • gut-brain axis (35 posts to June 2016)
  • gut microbiota (33 posts to June 2016)
  • gut microbiota dysbiosis (2 posts to March 2022)
  • gut microbiota transplants (1 post to October 2023) You need to be aware of this problem.

    • Pathogenic Mechanisms of Cerebral Ischemia and Potential Gut-Brain Axis-Oriented Therapeutic Strategies


    https://doi.org/10.1016/j.phymed.2025.157264Get rights and content

    Highlights

    • •
      The gut-brain axis regulates cerebral ischemia via neural/immune/microbial pathways.
    • •
      TCM protect brain by regulating gut and neuroinflammation.
    • •
      A new GBA mechanism and medicine strategy treat CI via flora is summarized.

    Abstract

    Background

    Cerebral ischemia is a serious cerebrovascular disease, and its pathogenesis is complex and involves a variety of pathological processes. In recent years, the theory of gut-brain axis has provided a new research perspective to reveal the synergistic pathological changes between brain and gut during cerebral ischemia. According to this theory, there is a bidirectional regulation mechanism between the central nervous system and gut microbiota, and the gut-brain axis plays a pivotal role in the occurrence and progression of cerebral ischemia. Therefore, drug intervention strategies based on gut-brain axis have gradually attracted attention. Existing studies have shown that, Chinese herbal medicines, compound prescriptions and Chinese patent medicines, can play potential therapeutic effects on cerebral ischemia by regulating intestinal flora, reducing neuroinflammation and oxidative stress. Despite the continuous progress of related research in recent years, the understanding of the role of gut-brain axis in cerebral ischemia is still patchy and lack of systematic summary.

    Purpose

    This article reviews the pathogenesis of cerebral ischemia regulated by the gut-brain axis and frontier drug intervention research based on this theory, in order to provide reference for follow-up research and clinical practice.
    Posted by at
    Labels: , , , ,

    No comments:

    Post a Comment

    Subscribe to: Post Comments (Atom)