Deans' stroke musings: Effects of Albumin, Uric Acid, Hemoglobin, and C-Reactive Protein Levels on Rehabilitation Outcomes in Stroke: A Retrospective Clinical Study

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, September 25, 2025

Effects of Albumin, Uric Acid, Hemoglobin, and C-Reactive Protein Levels on Rehabilitation Outcomes in Stroke: A Retrospective Clinical Study

Your competent? doctor has been working on Uric acid, albumin, C-reactive protein and hemoglobin a long time already, right? Oh no, you DON'T have a functioning stroke doctor, do you? And they still haven't been fired yet?

Uric acid (11 posts to February 2014)
albumin (5 posts to October 2011)
C-reactive protein(18 posts to October 2012)
hemoglobin A1c (1 post to December 2017)
hemoglobin levels (3 posts to February 2024)
hemoglobin-albumin cluster (1 post to July 2018)
hemoglobin-to-red cell distribution width ratio (1 post to March 2025)
oxygenated hemoglobin concentration (1 post to June 2017)
glycated hemoglobin levels (1 post to April 2025)

Effects of Albumin, Uric Acid, Hemoglobin, and C-Reactive Protein Levels on Rehabilitation Outcomes in Stroke: A Retrospective Clinical Study

y Selda Ciftci Inceoglu,1 Aylin Ayyildiz,2 Cansu Adikti,1 Banu Kuran1 1Department of Physical Medicine and Rehabilitation, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye 2Department of Physical Medicine and Rehabilitation, Basaksehir Cam & Sakura City Hospital, Istanbul, Türkiye

Objective:

The aim was to explain the relationship between recovery in motor functions and ambulation skills after stroke and albumin, uric acid, C-reactive protein (CRP), and hemoglobin levels.

Materials and Methods:

Patients who received inpatient rehabilitation in the physical medicine and rehabilitation (PM&R) clinic within the past 2 years were included in the study. Patients’ discharge report, albumin, CRP, uric acid, and hemoglobin levels were obtained from the blood tests taken during hospitalization through the hospital system. The relationship between Brunnstrom staging (BS) and functional ambulation category (FAC) assessments before treatment and on the 15th day of rehabilitation, and the initial albumin, CRP, uric acid, and hemoglobin levels was investigated.

Results:

The files of 135 patients were accessed. Six patients were excluded because they did not meet the inclusion criteria, and 4 patients were excluded because their data were incomplete. The study was completed with 125 patients. Albumin levels were low in 22 (17.6%) patients, and hemoglobin levels were low in 75 (60%) patients. CRP levels were above normal in 53 (42.4%) patients. When uric acid levels were examined, 1 (0.8%) patient was below normal, and 15 (12%) patients were above normal. There was no significant relationship between BS and albumin, CRP, uric acid, and hemoglobin levels (p>0.05). There was a significant positive relationship between improvements in FAC and albumin and hemoglobin levels (p<0.05).

Conclusion:

Post-stroke FAC recovery is associated with albumin and hemoglobin levels.

Keywords:

Albumin, C-reactive protein, Hemoglobin, Stroke, Uric acid

Address for correspondence: Selda Ciftci Inceoglu, Department of Physical Medicine and Rehabilitation, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye E-mail: seldavd@gmail.com ORCID ID: 0000-0002-0387-3558 Submitted: 19.05.2025 Revised: 20.05.2025 Accepted: 14.07.2025 Available Online: 12.09.2025 European Archives of Medical Research – Available online at www.eurarchmedres.org OPEN ACCESS This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. ABSTRACT European Archives of Medical Research DOI: 10.14744/eamr.2025.20082 Eur Arch Med Res 2025;41(3):183–192 ORIGINAL ARTICLE INTRODUCTION Stroke is a cerebrovascular disease (CVD) that causes loss of brain function due to interruption of blood flow to the brain or bleeding.[1] It is a significant health problem worldwide. It is a significant cause of morbidity and mortality acquired in adulthood.[2] Most patients develop hemiplegia, affecting upper extremity functions and ambulation skills.[3] Stroke re habilitation is the primary treatment option recommended for functional limitations and disabilities that occur after a stroke.[4] Cite this article as: Ciftci Inceoglu S, Ayyildiz A, Adikti C, Kuran B. Effects of Albumin, Uric Acid, Hemoglobin, and C-Reactive Protein Levels on Rehabilitation Outcomes in Stroke: A Retrospective Clinical Study. Eur Arch Med Res 2025;41(3):183–192.