Good luck getting this done correctly outside a research program! So, pretty much useless; EXCEPT YOU CAN NOW BLAME THE PATIENT for not following it correctly!
Cognitive Benefits of a Healthy Lifestyle Confirmed: LatAm-Fingers
LONDON — A structured, culturally adapted lifestyle intervention significantly improved global cognition over 2 years in older adults at increased risk for dementia across 11 Latin American countries, extending evidence that multidomain dementia prevention programs can be successfully adapted beyond high-income settings.
In the LatAm-FINGERS trial, older adults who received a structured multidomain lifestyle intervention experienced a 55% greater improvement in global cognition over 2 years than peers who received general lifestyle advice alone.
The intervention combined supervised exercise, dietary counseling, cognitive training, vascular risk management, and regular social support and coaching, while the comparison group received periodic health education and general lifestyle recommendations.

“The study is important because it shows that dementia risk reduction strategies can be implemented beyond high-income countries, when they are culturally adapted and delivered in a structured way,” lead investigator Lucia Crivelli, PhD, head of Neuropsychology at Fleni-CONICET in Buenos Aires, Argentina, told Medscape Medical News.
- Structured multidomain lifestyle intervention ↑ global cognition over 2 years.
- Benefit in 1065 older adults at ↑ dementia risk across 11 Latin American countries.
- Structured program: exercise + adapted MIND diet + cognitive training + vascular risk control + social support.
- Global cognition improved 0.31 vs 0.20 SD/year; between-group difference 0.11 SD/year.
- Greater gains in episodic memory, executive function, and processing speed; no CDR-SB difference.
“It also reinforces the idea that lifestyle-related risk factors are not marginal: They are central to brain health and may represent a major opportunity for prevention, particularly in regions such as Latin America, where the burden of modifiable risk factors is high,” Crivelli added
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