Deans' stroke musings: exosomes delivering drugs to brain

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, March 28, 2011

exosomes delivering drugs to brain

This might make it easier to deliver a lot of the drugs I mentioned in earlier posts to the brain.

exosomes delivering drugs to brain

A new way of delivering drugs to the brain has been developed by scientists at the University of Oxford.
They used the body's own transporters - exosomes - to deliver drugs in an experiment on mice.
The authors say the study, in Nature Biotechnology, could be vital for treating diseases such as Alzheimer's, Parkinson's and Muscular Dystrophy.
The Alzheimer's Society said the study was "exciting" and could lead to more effective treatments.
Research barrier

One of the medical challenges with diseases of the brain is getting any treatment to cross the blood-brain barrier.
The barrier exists to protect the brain, preventing bacteria from crossing over from the blood, while letting oxygen through.
However, this has also produced problems for medicine, as drugs can also be blocked.

So would this help get
tPA in;
nicotine;
marijuana;
magnesium;
viagra;
nitric oxide;
anti-depressants
tgf alpha;
lobster shells;
tumeric;
niacin;
caffeinol;
xenon gas;
drug that activated the sigma-1 receptor;
Docosahexaenoic acid (DHA), a component of fish oil?

All these possibilities just waiting to be further tested. Ask your doctor which ones s/he believes has the most promise and when they are going to start a clinical trial. Come on lets start the guilt trips on our medical staff.