Great, depression is rampant among stroke survivors. Ask your doctor if anti-depressants are enough to prevent shortening telomeres.
The CBSnews article here;
Depression may make our cells age faster
Ways around this problem talked about here;
Telomeres may shorten with depression but there are things you can do to protect them
The research the article is based upon is here;
Patients with major
depressive disorder (MDD) have an increased onset risk of aging-related
somatic diseases such as heart disease, diabetes, obesity and cancer.
This suggests mechanisms of accelerated biological aging among the
depressed, which can be indicated by a shorter length of telomeres. We
examine whether MDD is associated with accelerated biological aging, and
whether depression characteristics such as severity, duration, and
psychoactive medication do further impact on biological aging. Data are
from the Netherlands Study of Depression and Anxiety, including 1095
current MDD patients, 802 remitted MDD patients and 510 control
subjects. Telomere length (TL) was assessed as the telomere sequence
copy number (T) compared to a single-copy gene copy number (S) using
quantitative polymerase chain reaction. This resulted in a T/S
ratio and was converted to base pairs (bp). MDD diagnosis and MDD
characteristics were determined by self-report questionnaires and
structured psychiatric interviews. Compared with control subjects (mean
bp=5541), sociodemographic-adjusted TL was shorter among remitted MDD patients (mean bp=5459; P=0.014) and current MDD patients (mean bp=5461; P=0.012).
Adjustment for health and lifestyle variables did not reduce the
associations. Within the current MDD patients, separate analyses showed
that both higher depression severity (P<0.01) and longer symptom
duration in the past 4 years (P=0.01) were
associated with shorter TL. Our results demonstrate that depressed
patients show accelerated cellular aging according to a ‘dose–response’
gradient: those with the most severe and chronic MDD showed the shortest
TL. We also confirmed the imprint of past exposure to depression, as
those with remitted MDD had shorter TL than controls.
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