Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, July 19, 2016

Comprehensive cellular-resolution atlas of the adult human brain

Which one of these atlases is your doctor using to show you the damage to your brain and explain the disabilities that come from that? Do you get a cool 3d rendering of it?

The Human Brainnetome Atlas: A New Brain Atlas Based on Connectional Architecture

New brain atlas opens up alternative means for studying brain disorders

Stereoscopic Atlas of Intrinsic Brain Networks (SAIBN)

 

 


The latest here:

Comprehensive cellular-resolution atlas of the adult human brain

  1. Song-Lin Ding1,*,
  2. Joshua J. Royall1,
  3. Susan M. Sunkin1,
  4. Lydia Ng1,
  5. Benjamin A. C. Facer1,
  6. Phil Lesnar1,
  7. Angie Guillozet-Bongaarts1,
  8. Bergen McMurray1,
  9. Aaron Szafer1,
  10. Tim A. Dolbeare1,
  11. Allison Stevens2,
  12. Lee Tirrell2,
  13. Thomas Benner2,
  14. Shiella Caldejon1,
  15. Rachel A. Dalley1,
  16. Nick Dee1,
  17. Christopher Lau1,
  18. Julie Nyhus1,
  19. Melissa Reding1,
  20. Zackery L. Riley1,
  21. David Sandman1,
  22. Elaine Shen1,
  23. Andre van der Kouwe2,
  24. Ani Varjabedian2,
  25. Michelle Write2,
  26. Lilla Zollei2,
  27. Chinh Dang1,
  28. James A. Knowles3,
  29. Christof Koch1,
  30. John W. Phillips1,
  31. Nenad Sestan4,
  32. Paul Wohnoutka1,
  33. H. Ronald Zielke5,
  34. John G. Hohmann1,
  35. Allan R. Jones1,
  36. Amy Bernard1,
  37. Michael J. Hawrylycz1,
  38. Patrick R. Hof6,
  39. Bruce Fischl2 and
  40. Ed S. Lein1,*
DOI: 10.1002/cne.24080

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Keywords:

  • brain atlas;
  • cerebral cortex;
  • hippocampal formation;
  • thalamus;
  • hypothalamus;
  • amygdala;
  • cerebellum;
  • brainstem;
  • MRI;
  • DWI;
  • cytoarchitecture;
  • parvalbumin;
  • neurofilament protein;
  • RRIDs: AB_10000343;
  • AB_2314904;
  • SCR_014329

ABSTRACT

Detailed anatomical understanding of the human brain is essential for unraveling its functional architecture, yet current reference atlases have major limitations in terms of lack of whole-brain coverage, relatively low image resolution, and sparse structural annotation. We present the first digital human brain atlas to incorporate neuroimaging, high-resolution histology, and chemoarchitecture across a complete adult female brain, consisting of MRI, DWI, and 1356 large-format cellular resolution (1 µm/pixel) Nissl and immunohistochemistry anatomical plates. The atlas is comprehensively annotated for 862 structures, including 117 white matter tracts and several novel cyto- and chemoarchitecturally defined structures, and these annotations were transferred onto the matching MRI dataset. Neocortical delineations were done for sulci, gyri, and modified Brodmann areas to link macroscopic anatomical and microscopic cytoarchitectural parcellations. Correlated neuroimaging and histological structural delineation allowed fine feature identification in MRI data and subsequent structural identification in MRI data from other brains. This interactive online digital atlas is integrated with existing Allen Institute for Brain Science gene expression atlases and is publicly accessible as a resource for the neuroscience community. This article is protected by copyright. All rights reserved.

 



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