http://stroke.ahajournals.org/content/48/3/611?etoc=
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Abstract
Background and Purpose—We examined the associations of individual and combined lifestyle factors with early adverse stroke outcomes.
Methods—A
total of 82 597 patients were identified from nationwide registries.
Lifestyle factors at the time of stroke admission included body mass
index (kg/m2), smoking habits, and alcohol intake, which were
grouped (healthy, moderately healthy, moderately unhealthy, and
unhealthy). The associations between lifestyle and outcomes were
examined using multivariable regression.
Results—A
total of 18.3% had a severe stroke, 7.8% pneumonia, 12.5% urinary tract
infection, and 9.9% died within 30 days. The association between
lifestyle, stroke severity, and mortality, respectively, differed
according to sex. Unhealthy lifestyle was associated with lower risk of
severe stroke (adjusted odds ratio [OR], 0.73; 95% confidence interval
[CI], 0.63–0.84) and 30-day mortality among men (adjusted OR, 0.71; 95%
CI, 0.58–0.87), but not among women (severe stroke: adjusted OR, 1.14;
95% CI, 0.85–1.55, and mortality: adjusted OR, 1.34; 95% CI, 0.90–1.99).
No sex differences were found for pneumonia and urinary tract
infection. Unhealthy lifestyle was not associated with a statistically
significant increased risk of developing in-hospital pneumonia (adjusted
OR, 1.30; 95% CI, 0.98–1.73) or urinary tract infection (adjusted OR,
0.98; 95% CI, 0.72–1.33). Underweight was associated with a higher
30-day mortality (men: adjusted OR, 1.71; 95% CI, 1.50–1.96, and women:
adjusted OR, 1.46; 95% CI, 1.34–1.60).
Conclusions—Healthy
lifestyle was not associated with a lower risk of adverse stroke
outcomes, in particularly among men. However, underweight may be a
particular concern being associated with an increased risk of adverse
outcomes among both sexes.
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