Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Tuesday, February 28, 2017

Stroke Recovery and Rehabilitation Research Issues, Opportunities, and the National Institutes of Health StrokeNet

Euphemisms abound, never in here do they actually directly mention any of the fucking problems in stroke.
http://stroke.ahajournals.org/content/48/3/813?etoc=
Steven C. Cramer, Steven L. Wolf, Harold P. Adams, Daofen Chen, Alexander W. Dromerick, Kari Dunning, Caitlyn Ellerbe, Andrew Grande, Scott Janis, Maarten G. Lansberg, Ronald M. Lazar, Yuko Y. Palesch, Lorie Richards, Elliot Roth, Sean I. Savitz, Lawrence R. Wechsler, Max Wintermark, Joseph P. Broderick
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Introduction

Stroke is the second leading cause of death and the third leading cause of disability-adjusted life years worldwide. Although numerous therapies have been developed over the past 10 years to treat acute ischemic stroke, the stark reality remains that only 5% of these patients are so treated in the United States,1 in part, because of treatment window times <3 to 6 hours post-onset, and many of these 5% nonetheless have significant long-term disability. Acute treatment options after hemorrhagic stroke remain limited.2
In parallel with efforts to further develop acute stroke interventions, researchers are studying recovery and rehabilitation treatments, which can have a treatment time window measured in days, weeks, or months poststroke. To achieve this goal, therapies aim to maximize function in brain areas that survive the stroke or provide compensatory approaches to improve overall function. Strategies targeting recovery and rehabilitation must be seen as distinct from acute stroke therapies, such as reperfusion or neuroprotection, where the strategy is to limit the severity of ischemic injury, including preserving penumbral tissue and reducing infarct size.
Preclinical and translational research have successfully identified numerous molecular and physiological events spontaneously arising in the nervous system during the days-to-weeks after an infarct, and, subsequently, potential restorative therapies that target these events to improve long-term behavioral outcomes.3,4 In parallel, a burgeoning volume of data from human subjects has emerged regarding mechanisms of recovery from stroke. Together, these efforts inform translation into clinical studies for several classes of therapy, including small molecules, growth factors, stem cells, monoclonal antibodies, brain stimulation, robotics and other devices, cognitive strategies, intensive training, and telerehabilitation.5,6
The majority of patients with stroke survive the initial event but go on to live with significant disability for many years. Indeed, there are >7 million stroke survivors …
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