Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 12345 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Deans' stroke musings
Changing stroke rehab and research worldwide now.Time is Brain!Just think of all thetrillions and trillions of neuronsthateach daybecause there areeffective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group. My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html
Tuesday, February 28, 2017
Vessel Wall Enhancement and Blood–Cerebrospinal Fluid Barrier Disruption After Mechanical Thrombectomy in Acute Ischemic Stroke
Are you people that unknowing and out-of-date that you aren't even considering the neuronal cascade of death as the cause? Remedial slaps upside the head or rapped knuckles from your great stroke association president. No wonder we don't get anywhere, we have no fucking idea the problem we are trying to solve. February 7, 2017
Arturo Renú, Carlos Laredo, Antonio Lopez-Rueda, Laura Llull, Raúl Tudela, Luis San-Roman, Xabier Urra, Jordi Blasco, Juan Macho, Laura Oleaga, Angel Chamorro, Sergio Amaro
Originally publisheform below to view the
article. Access to this article can also be purchased.
Background and Purpose—Less
than half of acute ischemic stroke patients treated with mechanical
thrombectomy obtain permanent clinical benefits. Consequently, there is
an urgent need to identify mechanisms implicated in the limited efficacy
of early reperfusion. We evaluated the predictors and prognostic
significance of vessel wall permeability impairment and its association
with blood–cerebrospinal fluid barrier (BCSFB) disruption after acute
stroke treated with thrombectomy.
prospective cohort of acute stroke patients treated with stent
retrievers was analyzed. Vessel wall permeability impairment was
identified as gadolinium vessel wall enhancement (GVE) in a 24- to
48-hour follow-up contrast-enhanced magnetic resonance imaging, and
severe BCSFB disruption was defined as subarachnoid hemorrhage or
gadolinium sulcal enhancement (present across >10 slices). Infarct
volume was evaluated in follow-up magnetic resonance imaging, and
clinical outcome was evaluated with the modified Rankin Scale at day 90.
total of 60 patients (median National Institutes of Health Stroke Scale
score, 18) were analyzed, of whom 28 (47%) received intravenous
alteplase before mechanical thrombectomy. Overall, 34 (57%) patients had
GVE and 27 (45%) had severe BCSFB disruption. GVE was significantly
associated with alteplase use before thrombectomy and with more stent
retriever passes, along with the presence of severe BCSFB disruption.
GVE was associated with poor clinical outcome, and both GVE and severe
BCSFB disruption were associated with increased final infarct volume.
findings may support the clinical relevance of direct vessel damage and
BCSFB disruption after acute stroke and reinforce the need for further
improvements in reperfusion strategies. Further validation in larger
cohorts of patients is warranted.