Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Monday, April 3, 2017

Cocaine use and risk of ischemic stroke in young adults

So don't do cocaine.
https://www.mdlinx.com/internal-medicine/medical-news-article/2016/03/30/cocaine-hypertension-odds-ratio-stroke-young/6604505/?
Stroke
Cheng YC, et al. –
This article is featured in Smartest Doc. See if you can answer related questions.

Although case reports have long identified a temporal association between cocaine use and ischemic stroke (IS), few epidemiological studies have examined the association of cocaine use with IS in young adults, by timing, route, and frequency of use. The data are consistent with a causal association between acute cocaine use and risk of early–onset IS.

Methods

  • A population-based case-control study design with 1090 cases and 1154 controls was used to investigate the relationship of cocaine use and young-onset IS.
  • Stroke cases were between the ages of 15 and 49 years.
  • Logistic regression analysis was used to evaluate the association between cocaine use and IS with and without adjustment for potential confounders.

Results

  • Ever use of cocaine was not associated with stroke with 28% of cases and 26% of controls reporting ever use.
  • In contrast, acute cocaine use in the previous 24 hours was strongly associated with increased risk of stroke (age-sex-race adjusted odds ratio, 6.4; 95% confidence interval, 2.2-18.6).
  • Among acute users, the smoking route had an adjusted odds ratio of 7.9 (95% confidence interval, 1.8-35.0), whereas the inhalation route had an adjusted odds ratio of 3.5 (95% confidence interval, 0.7-16.9).
  • After additional adjustment for current alcohol, smoking use, and hypertension, the odds ratio for acute cocaine use by any route was 5.7 (95% confidence interval, 1.7-19.7).
  • Of the 26 patients with cocaine use within 24 hours of their stroke, 14 reported use within 6 hours of their event.

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