Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, November 21, 2011

Stroke recovery depends on the exchange of information between the brain hemispheres

I had not heard of anything like this before so I wonder in my case if the damage to white matter is causing some of the hemisphere communication problems. Or should I just stick to Occams razor and attribute it to dead brain.
http://www.psypost.org/2011/11/stroke-recovery-depends-on-the-exchange-of-information-between-the-brain-hemispheres-8121
The structure of the corpus callosum, a thick band of nerve fibres that connects the two halves of the brain with each other and in this way enables the rapid exchange of information between the left and right hemispheres, plays an important role in the regaining of motor skills following a stroke. A study currently published in the journal Human Brain Mapping has shown that in stroke patients with particularly severely impaired hand movement, this communication channel between the two brain hemispheres in particular was badly damaged.

In order to relate brain function and anatomical structure with each other, in this study the scientists from the Max Planck Institute for Neurological Research and the Department of Neurology at the University Hospital of Cologne combined two imaging methods. They asked stroke patients to make a simple tapping movement using the hand affected by the stroke and recorded their brain activity using functional magnetic resonance imaging. The data obtained in this way were then compared with data from healthy subjects. As expected from previous test results, compared with the control group, the stroke patients recorded a lower tapping speed and increased brain activity on both sides of the brain. “The increased activity in the healthy brain hemisphere, in particular, points to the impaired processing of motor programs between the two brain hemispheres,” explains Christian Grefkes, head of the research study.

In order to demonstrate the structural connection between brain areas, the Cologne researchers used diffusion-based magnetic resonance imaging (dMRI), which can be used to reconstruct longer stretches of nerve fibres. dMRI is based on the principle that cell elements, such as the membrane or extensions, inhibit the spread of water molecules thereby preventing them from diffusing randomly in all directions. Consequently, parallel nerve fibres can be clearly identified using dMRI. Compared to the healthy control group, the stroke patients had lower diffusion values in the corpus callosum region. This would indicate that this interhemispheric communications connection was damaged by the stroke. The most significant deviations from the values of the control group were observed in patients with more severe motor defects and increased activity in the healthy brain hemisphere.

Therefore, in addition to cell death in the actual stroke area, damage to a very distant connection structure plays a crucial role in the inability of stroke patients to fully regain their original motor capacities. “This is why, we are currently examining whether we can regenerate the communication between the brain hemispheres through early and regular stimulation treatment. Our long-term aim is to improve motor deficits in stroke patients,” says Grefkes.

1 comment:

  1. Interesting concept...could apply to me. I have a large piece of dead brain, but limited remaining physical deficits. I think my corpus callosum was not damaged. Most of my damage is deep right side. My recovery has been amazing....like a miracle..Im extremely thankful but sometimes wonder how I got so lucky. I always sorta thought it was the location of the damage.

    ReplyDelete