So when are our doctors going to put 2 and 2 together and give curcumin to us as a neuroprotective in the first days as listed here:
http://oc1dean.blogspot.com/2011/03/tumeric-and-stroke-rehab.html
The delivery article here:
http://www.dovepress.com/article_11689.t14230688
Abstract: We investigated
flexible liposomes as a potential oral drug delivery system. However,
enhanced membrane fluidity and structural deformability may necessitate
liposomal surface modification when facing the harsh environment of the
gastrointestinal tract. In the present study, silica-coated flexible
liposomes loaded with curcumin (CUR-SLs) having poor water solubility as
a model drug were prepared by a thin-film method with homogenization,
followed by the formation of a silica shell by the sol-gel process. We
systematically investigated the physical properties, drug release
behavior, pharmacodynamics, and bioavailability of CUR-SLs. CUR-SLs had a
mean diameter of 157 nm and a polydispersity index of 0.14, while the
apparent entrapment efficiency was 90.62%. Compared with curcumin-loaded
flexible liposomes (CUR-FLs) without silica-coatings, CUR-SLs had
significantly higher stability against artificial gastric fluid and
showed more sustained drug release in artificial intestinal fluid as
determined by in vitro release assays. The bioavailability of CUR-SLs
and CUR-FLs was 7.76- and 2.35-fold higher, respectively, than that of
curcumin suspensions. Silica coating markedly improved the stability of
flexible liposomes, and CUR-SLs exhibited a 3.31-fold increase in
bioavailability compared with CUR-FLs, indicating that silica-coated
flexible liposomes may be employed as a potential carrier to deliver
drugs with poor water solubility via the oral route with improved
bioavailability.
Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 29,112 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.
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