My take on this. If it is relaxing blood vessels then maybe something like this needs to be researched if the reason it relaxes blood vessels is that pericytes let go. If so then it could be used in hyperacute therapy to open the capillaries that have been closed down by clamping pericytes. Have your researcher get back to you with the answer.
http://www.medpagetoday.com/Cardiology/CHF/36635
The mortality reduction seen in acute heart failure with the novel
blood vessel relaxer serelaxin may be a real effect from reduced
end-organ damage and faster decongestion, exploratory analysis of the
RELAX-AHF trial data suggested.
Safety results from that trial
indicated a 37% reduction at 6 months in both cardiovascular death risk
and in all-cause mortality with numbers needed to treat of less than
30.
The effect was virtually identical in combined analysis of the phase
II and phase III studies with the drug (hazard ratio 0.62 for all-cause
death, P=0.0076), Marco Metra, MD, of the University of Brescia, Italy, and colleagues reported online in the Journal of the American College of Cardiology.
Serelaxin treatment was associated with reduced markers of cardiac,
renal, and liver damage and with less congestion at day two of the heart
failure admission, which all correlated with 6-month mortality
"providing a potential mechanism for the improved survival of
serelaxin-treated patients."
The rest at the link
Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 29,286 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke. DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.
Friday, December 28, 2012
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