Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Tuesday, September 13, 2016

Changes in Middle Cerebral Artery Blood Flow Velocity During Sonolysis Using a Diagnostic Transcranial Probe With a 2-MHz Doppler Frequency in Healthy Volunteers

    It sounded good but didn't work. Better velocity of MCA blood flow would probably drive more oxygen to the localized brain tissue.

    1. David Školoudík, MD, PhD, FESO
    + Author Affiliations
    1. Department of Neurology, Hospital Třinec-Sosna, Třinec, Czech Republic (P.B.); Comprehensive Stroke Center, Department of Neurology, Ostrava University Medical Faculty and University Hospital, Ostrava, Czech Republic (M.K., D.Šk.); Comprehensive Stroke Center, Department of Neurology, Faculty of Medicine and Dentistry, Palacký University and University Hospital, Olomouc, Czech Republic (R.H., D.Ša., P.K., D.Šk.); and Department of Medical Biophysics, Faculty of Medicine and Dentistry, Institute of Molecular and Translational Medicine, Palacký University, Olomouc, Czech Republic (K.L.).
    1. Address correspondence to David Školoudík, MD, PhD, FESO, Comprehensive Stroke Center, Department of Neurology, University Hospital, 17 Listopadu 1790, CZ-708 00 Ostrava, Czech Republic. E-mail: skoloudik@hotmail.com

    Abstract

    Objectives—Ultrasound has various biological effects in the human body. The effects of continuous monitoring with ultrasound (sonolysis) on vasodilatation of the radial artery were described recently. We wanted to ascertain whether similar changes in the blood flow velocity during sonolysis could also be detected in the middle cerebral artery.
    Methods—Fifteen healthy volunteers (6 male and 9 female; age range, 23–68 years; mean ± SD, 47.1 ± 15.1 years) were subjected to 1 hour of middle cerebral artery sonolysis using a diagnostic transcranial probe with a 2-MHz Doppler frequency and measurement of the blood flow velocity at 2-minute intervals. During a second session, a flow curve was recorded for 10 seconds at 2-minute intervals. The peak systolic velocity, end-diastolic velocity, mean flow velocity, pulsatility index, and resistive index were recorded during both measurements.
    Results—Irregular changes in the measured blood flow parameters were recorded during both sessions. Changes in particular hemodynamic parameters during both measurements were similar. The changes in the peak systolic velocity, end-diastolic velocity, mean flow velocity, pulsatility index, and resistive index were not significantly different between the two measurements (P < .05 in all cases).
    Conclusions—As opposed to sonolysis of the radial artery, sonolysis of the middle cerebral artery using a diagnostic 2-MHz frequency in healthy volunteers did not lead to changes in the flow curve or peripheral vasodilatation.

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