Deans' stroke musings: This Legal Drug Could Protect Brain From Ageing

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, September 26, 2016

This Legal Drug Could Protect Brain From Ageing - Nicotine

I'm going to do the nicotine patch after my next stroke. What is your doctor having you do?
ANYTHING AT ALL? Does your doctor know anything at all about this? Or does your doctor read NO research at all?

Nicotine Holds Promise for Stronger Stroke Recovery

Nicotine Patch Appears To Help Mild Cognitive Loss

The latest here:

This Legal Drug Could Protect Brain From Ageing - Nicotine

Could cigarettes contain the latest clue to an anti-ageing drug?

Nicotine could help to protect the brain from Alzheimer’s and Parkinson’s disease, new research finds.
The substance — when given independently from tobacco — could help to protect the ageing brain.
The neuroprotective effect of nicotine could be down to its well-known quality of reducing appetite.
For the study, the researchers gave varying levels of nicotine to mice in their drinking water.
There was no evidence, though, that it caused anxiety, which the researchers were concerned would be the case.
Dr Ursula Winzer-Serhan, who led the research, said:

“Some people say that nicotine decreases anxiety, which is why people smoke, but others say it increases anxiety.
The last thing you would want in a drug that is given chronically would be a negative change in behavior.
Luckily, we didn’t find any evidence of anxiety: Only two measures showed any effect even with high levels of nicotine, and if anything, nicotine made animal models less anxious.”

The mice given the highest levels of nicotine ate the least and gained the least weight.

Dr Winzer-Serhan cautioned:

“I want to make it very clear that we’re not encouraging people to smoke.
Even if these weren’t very preliminary results, smoking results in so many health problems that any possible benefit of the nicotine would be more than cancelled out.
However, smoking is only one possible route of administration of the drug, and our work shows that we shouldn’t write-off nicotine completely.”

The next step for the researchers is to test whether nicotine has a an anti-ageing effect.
Dr Winzer-Serhan said:

“Although the results are intriguing, we would need large-scale clinical trials before suggesting anyone change their behavior.
At the end of the day, we haven’t proven that this addictive drug is safe — and it certainly isn’t during childhood or adolescence — or that the benefits outweigh the potential risks.”

The study was published in the Journal of Toxicology (Huang et al., 2016).