I can't figure this one out at all. Caffeine = shorter, coffee = longer. Does not compute.
Caffeine consumption and telomere length in men and women of the National Health and Nutrition Examination Survey (NHANES)
Nutrition & Metabolism, 02/03/2017
Tucker
LA – In this National Health and Nutrition Examination Survey (NHANES),
the researchers assessed the relationship between caffeine intake and
coffee consumption and leukocyte telomere length in men and women. The
results obtained from the study indicate that caffeine consumption
accounts for shorter telomeres in U.S. adults, independent of numerous
covariates, whereas coffee intake predicts longer telomeres.
Methods
- An aggregate of 5826 adults from the National Health and Nutrition Examination Survey (NHANES) were studied cross-sectionally.
- Utilizing the quantitative polymerase chain reaction method, telomere length was compared to standard reference DNA.
- After that, caffeine intake from foods and beverages and coffee consumption were measured utilizing a validated, multi-pass, computer-assisted, 24-h recall system administered by NHANES interviewers.
- The following covariates were controlled: age, gender, race, marital status, education, housing, smoking, BMI, physical activity, alcohol use, and coffee intake (or caffeine consumption).
Results
- The results of this study showed that caffeine consumption was inversely related to telomere length (F = 15.1, P = 0.0005).
- For each 100 mg of caffeine consumed, telomeres were 35.4 base pairs shorter, after adjusting for the covariates.
- For each 100 mg of caffeine consumed among coffee drinkers only, telomeres were 36.7 base pairs shorter (F = 9.0, P = 0.0054), and among non-coffee drinkers only, 40.0 base pairs shorter (F = 8.5, P = 0.0067).
- Findings revealed that coffee intake was positively related to telomere length (F = 12.6, P = 0.0013), independent of the covariates.
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