Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Friday, February 3, 2017

Caffeine consumption and telomere length in men and women of the National Health and Nutrition Examination Survey (NHANES)

I can't figure this one out at all. Caffeine = shorter, coffee = longer. Does not compute.
https://www.mdlinx.com/family-medicine/medical-news-article/2017/02/03/cell-aging-coffee-stimulant-leukocyte-dna/7042950/?
Nutrition & Metabolism, 02/03/2017
Tucker LA – In this National Health and Nutrition Examination Survey (NHANES), the researchers assessed the relationship between caffeine intake and coffee consumption and leukocyte telomere length in men and women. The results obtained from the study indicate that caffeine consumption accounts for shorter telomeres in U.S. adults, independent of numerous covariates, whereas coffee intake predicts longer telomeres.

Methods

  • An aggregate of 5826 adults from the National Health and Nutrition Examination Survey (NHANES) were studied cross-sectionally.
  • Utilizing the quantitative polymerase chain reaction method, telomere length was compared to standard reference DNA.  
  •  After that, caffeine intake from foods and beverages and coffee consumption were measured utilizing a validated, multi-pass, computer-assisted, 24-h recall system administered by NHANES interviewers.
  • The following covariates were controlled: age, gender, race, marital status, education, housing, smoking, BMI, physical activity, alcohol use, and coffee intake (or caffeine consumption).   

Results

  • The results of this study showed that caffeine consumption was inversely related to telomere length (F = 15.1, P = 0.0005).  
  •  For each 100 mg of caffeine consumed, telomeres were 35.4 base pairs shorter, after adjusting for the covariates.
  • For each 100 mg of caffeine consumed among coffee drinkers only, telomeres were 36.7 base pairs shorter (F = 9.0, P = 0.0054), and among non-coffee drinkers only, 40.0 base pairs shorter (F = 8.5, P = 0.0067).
  • Findings revealed that coffee intake was positively related to telomere length (F = 12.6, P = 0.0013), independent of the covariates.   
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