Do you really expect the thousands of doctors out there that need to impart this evidence to their patients to all do it correctly? And your doctor is one of those that can do it correctly?
We need a fucking protocol, damn it all, our stroke medical leaders are so fucking incompetent that it is lucky if they even know what the word protocol means.
- In this study, the researchers measured plasma 25-hydroxyvitamin D [25(OH)D] with the utilization of high-performance liquid chromatography–mass spectrometry, assessed dietary vitamin D intake with the use of 7-d dietary records, and created a vitamin D–synthesis genetic risk score (GRS) at baseline (1991–1995) in a cohort of 1182 Swedish men (mean age: 71 y).
- In a maximum of 18 y (median: 12 y) of follow-up, 116 men developed Alzheimer disease, 64 men developed vascular dementia, and 250 men developed all-cause dementia.
- An additional 80 men declined in cognitive function as evaluated with the utilization of the Mini-Mental State Examination.
- Adjusted HRs and ORs were figured with the utilization of Cox and logistic regressions.
- The results of this study showed that the mean ± SD plasma 25(OH)D concentration was 68.7 ± 19.1 nmol/L.
- Plasma 25(OH)D, dietary vitamin D intake, and vitamin D–synthesis GRS were not related to any cognitive outcomes (crude and adjusted HRs and ORs were ∼1.0 for all continuous exposures).
- It was observed in the findings that the adjusted HR for all-cause dementia was 0.88 (95% CI: 0.59, 1.31) in men with plasma 25(OH)D concentrations ≤50 compared with &
- >75 nmol/L.
- Findings revealed that the adjusted HR for all-cause dementia was 0.92 (95% CI: 0.63, 1.32) for the lowest compared with highest tertiles of vitamin D intake.
- In addition, the adjusted HR for the continuous GRS for all-cause dementia was 1.04 (95% CI: 0.91, 1.19).