Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, June 11, 2019

Study aims to optimize device implantation in patients with atrial fibrillation and stroke risk

If you have atrial fibrillation then either you or your doctor need to be following this. I don't like the 1/3 chance of having a stroke so your doctor needs to  have a prevention protocol for that. NOT a guideline, a protocol.

Study aims to optimize device implantation in patients with atrial fibrillation and stroke risk


According to clinical studies, about a third of patients with atrial fibrillation will suffer a stroke during their lifetime. Between 70 and 90% of these strokes are caused by a thrombus formed in the left atrial appendage.
In patients with contraindications to oral anticoagulants, a left atrial appendage occluder (LAAO) is often implanted to prevent blood flow entering in the LAA. But this strategy is not without problems and often the success of the device depends on the clinician's experience. Implementation can even lead to blood clots outside the device, eventually leading to stroke if not treated.
The aim of a study, published in March in Frontiers in Physiology, was to develop tools based on biophysical models and interactive interfaces to optimize LAAO device therapies. The study was led by Òscar Camara, a researcher with the Physense Research Group, which is a part of the BCN MedTech Unit at the UPF Department of Information and Communication Technologies (DTIC).
A study that summarizes the good work of our research team over the past three years and is part of the bachelor's degree final project in Biomedical Engineering by Ainhoa M. Aguado, first author of the study."
Òscar Camara

To obtain the most appropriate LAAO configurations for a given patient-specific LAA morphology, the researchers created a web-based 3D interactive virtual implantation platform called VIDAA. Then, based on the features of the shape of the patient's appendage, the researchers calculated the most promising LAAO device.
Using the geometric and anatomic data of the patient's left atrial appendage, together with the most suitable ad hoc device, volumetric meshes were built to run computational fluid dynamics simulations. Thus the researchers were able to assess estimated blood flow patterns after device implantation.
Thus, by combining the VIDAA platform with computational simulations it has been possible to identify the LAAO configurations associated to a lower risk of thrombus formation and also to reveal that the positioning of the device is a key element in the creation of regions with turbulent blood flows after implantation.
Source:
Universitat Pompeu Fabra - Barcelona
Journal reference:
Aguado,A.M. et al. (2019) In silico Optimization of Left Atrial Appendage Occluder Implantation Using Interactive and Modeling Tools. Frontiers in Physiology. doi.org/10.3389/fphys.2019.00237

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