Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 27,840 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain!trillions and trillions of neuronsthatDIEeach day because there areNOeffective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.
Saturday, January 25, 2020
Neuroplasticity and cognitive benefits associated with chronic intranasal oxytocin administration in aging
Would this help stroke survivors? We'll never know since we have NO STROKE LEADERSHIP and NO STROKE STRATEGY.
Stockholm University, Faculty of Social Sciences, Department of Psychology, Biological psychology.
Lin, Tian
Lussier, Desiree
Show others and affiliations
2019 (English)Conference paper, Oral presentation only (Other academic)
Abstract [en]
Oxytocin (OT) is a
crucial chemical modulator of social behavior, and intranasal OT
administration has potential as treatment for social deficits.
Considerably less is known about OT’s effects on non-social cognition, a
functional domain of particular relevance in aging. Brain mechanisms
underlying OT’s benefits are not well understood but recent animal work
suggests that repeated OT administration induces brain changes. To test
this neuroplastic role of OT on the human brain and its potential for
cognitive improvement in aging, we conducted a randomized double-blind
study in older men (> 56 years), with 34 participants
self-administering either 24 IUs OT or placebo (P) twice daily. Before
and after 4-weeks intranasal administration, participants underwent MRI
and processing speed assessment. Using voxel-based morphometry, gray
matter (GM) volume was measured on T1-weighted anatomical images. Age,
education, physical health, and image quality served as covariates and
family-wise error rate determined statistical significance in regions of
interest. Analyses were performed without awareness of the assigned
treatment labels. Significant interactions between treatment (OT vs. P)
and time (pre- vs. post-intervention) on GM volume for left amygdala,
hippocampus, and putamen suggested increased regional GM volume
following OT but not P. Further, OT-induced enlargement in putamen was
associated with improved processing speed, while there was no
brain−behavior correlation in the P group. These findings support the
notion that amygdala, hippocampus, and putamen are key targets of OT’s
neuroplastic potential on the human brain and chronic OT administration
may constitute a potential treatment in counteracting cognitive decline
in aging.
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