WRONG, WRONG, WRONG! Your definition of effective is wrong. recanalization is not the goal. 100% recovery is the goal. Your tyranny of low expectations is showing in all its glory.
Mechanical thrombectomy is effective if implemented in public health systems in LMIC as Brazil
January 2017Journal of stroke and cerebrovascular diseases: the official journal of National Stroke Association 26(3)
Abstract and Figures
Background:
Brazil is a developing country struggling to reduce its extreme social
inequality, which is reflected on shortage of health-care
infrastructure, mainly to the low-income class, which depends
exclusively on the public health system. In Brazil, less than 1% of
stroke patients have access to intravenous thrombolysis in a stroke
unit, and constraints to the development of mechanical thrombectomy in
the public health system increase the social burden of stroke.
Objective:
Report the feasibility of mechanical thrombectomy as part of routine
stroke care in a Brazilian public university hospital.
Methods:
Prospective data were collected from all patients treated for acute
ischemic stroke with mechanical thrombectomy from June 2011 to March
2016. Combined thrombectomy was performed in eligible patients for
intravenous thrombolysis if they presented occlusion of large artery.
For those patients ineligible for intravenous thrombolysis, primary
thrombectomy was performed as long as there was no evidence of
significant ischemia for anterior circulation stroke (Alberta Stroke
Program Early CT score >6) within a 6-hour time window, and also for
those patients with wake-up stroke or posterior circulation stroke,
regardless of the time of symptoms onset.
Results:
A total of 161 patients were evaluated, resulting in an overall
successful recanalization rate of 76% and symptomatic intracranial
hemorrhage rate of 6.8%. At 3 months, 36% of the patients had modified
Rankin Scale score less than or equal to 2. The overall mortality rate
was 23%.
Conclusion:
Our study, the first ever large series of mechanical thrombectomy in
Brazil, demonstrates acceptable efficacy and safety results, even under
restricted conditions outside the ideal scenario of trial studies.
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