Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Sunday, November 11, 2012

Palm tocotrienols can prevent brain cell death after stroke

The title doesn't correspond to the article, it seems to reduce White matter lesions as a preventative rather than as a post stroke therapy.  Tocotrienols are a specialized form of vitamin E, you won't get them in standard drug store vitamins. No self-medication, that what your doctors are paid for.
I wrote about this a year and a half ago like this;
So here goes:

What are they? A natural component of Vitamin E that is found in barley, rice bran and palm oil products. Your standard vitamin E supplements only contain the tocopherols.
This report suggests that a level of this vitamin E can protect the brain after a stroke. But it takes about eight to 10 weeks of supplementation to build up to an adequate level in your system. For most Asians having a rice diet they would naturally have this.
Palm tocotrienols can prevent brain cell death after stroke

Researchers led by Professor Yuen Kah Hay of Universiti Sains Malaysia (USM) recently found that palm tocotrienols can protect brain cells in the event of a stroke.
“This breakthrough research suggests that taking 200mg of palm Researchers led by Professor Yuen Kah Hay of Universiti Sains Malaysia (USM) recently found that palm tocotrienols can protect brain cells in the event of a stroke.
“This breakthrough research suggests that taking 200mg of palm tocotrienols twice daily as a preventative can prevent brain cells from dying in the event of a stroke, which may translate to disability or survival benefits to the patients,” Professor Yuen said during a talk at a hotel here recently.
And considering stroke is the third biggest killer in Malaysia after heart disease and cancer, palm tocotrienols may bring benefits to the millions affected by this condition.
Professor Yuen and his team commenced the clinical trial after promising results were obtained in an American study which elucidated palm tocotrienols to be involved in the cell death signaling pathway to prevent neuronal cell death.
The researchers in America published their result after experimenting on genetically modified mice that are prone to stroke, as well as on canines, showing palm tocotrienols could minimize neuronal cell damage.
He said that 200 human volunteers with white matter lesions (WML), which are oxygen-starved brain cells, were recruited in the study led by him.
The placebo-controlled, randomized, double-blind clinical trial, which commenced in January, 2008, continued for two years.
At the end of the first year, the researchers found those taking 200mg of palm tocotrienols orally twice a day showed small increase in the WML volume, whereas those in the placebo group showed seven times more increase in WML volume.
“The placebo group continued to show further increases in the volume of lesions in the second year. Those on palm tocotrienols, however, showed a decrease.”
“The evidence we have now suggests that if people take it as a neuroprotective supplement, it can prevent brain cells from dying in the event of a stroke, and also stimulate the reconstruction of blood vessels after,” he said.
The encouraging results of the neuroprotective agent – palm tocotrienols, have led the Performance Management and Delivery Unit (PEMANDU) to fund a similar trial on diabetic patients, he said.
Meanwhile, USM researcher, Dr Enrico Magosso spoke on fatty liver and how this was a lifestyle disease.
“It is a progressive disease and affects between 10 percent and 30 percent of the world population. It is expected to become a major reason for transplant in the US, and patients with fatty liver are more likely to die from stroke,” he said.
He mentioned that in his study, he has found that tocotrienols has been effective in the prevention treatment of fatty liver.

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