Deans' stroke musings: Different Stages of Platelet Adhesion to the Site of Vascular Injury

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, January 18, 2013

Different Stages of Platelet Adhesion to the Site of Vascular Injury

See what this changes about your blood thinning from your doctor.
http://scholar.google.com/scholar_url?hl=en&q=http://www.ijbc.ir/browse.php%3Fa_id%3D349%26slc_lang%3Den%26sid%3D1%26ftxt%3D1&sa=X&scisig=AAGBfm1NSIJ29JuI8RU45NjsvCaS-cMqvg&oi=scholaralrt
Abstract
Platelet activation and adhesion to the site of vascular injury is a dynamic process comprising reversible and irreversible
phases. Platelet adhesion typically occurs in a multi-step process similar to the selectin/integrin-mediated adhesion
of neutrophils. This phenomenon is highly regulated and influenced by the cross-talk between platelets and injured
endothelium. This cross-talk involves a variety of mediators including adhesion molecules and receptors, agonists,
chemokines, shed proteins and various proinflammatory lipids.
This review briefly discuses the main adhesion molecules and receptors involved in both reversible and irreversible
phases of platelet adhesion to the site of vascular injury, leading to a better characterization of the multistep
mechanisms of thrombus formation.