Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation June 2004
- Forty-nine sedentary older adults (age: 64±1 years), free of overt major clinical disease, were randomized to HIIT (n=17), MICT (n=18) or non-exercise controls (CONT; n=14).
- HIIT (4x4 minutes at 90% of peak heart rate interspersed with 3x3 minutes active recovery at 70% of peak heart rate) and isocaloric MICT (70% of peak heart rate) were conducted on an all-extremity non-weight-bearing ergometer, 4 days/week, for 8 weeks under supervision.
- Aortic (carotid to femoral; cfPWV) and common carotid artery compliance were evaluated at pre- and post-intervention.
- cfPWV improved by 0.5 m/sec in MICT (P=0.04) but did not significantly alter in HIIT and CONT (P>0.05).
- Carotid artery compliance improved by 0.03 mm2/mmHg in MICT (P=0.001), while it remained unchanged in HIIT and CONT (P>0.05).
- Improvements in arterial stiffness in response to MICT were not confounded by changes in aortic or brachial blood pressure, heart rate, body weight, total and abdominal adiposity, blood lipids or aerobic fitness.