http://nutritionj.biomedcentral.com/articles/10.1186/s12937-017-0232-y
- Jeeyoo Lee,
- Ji-Eun Lee and
- Yuri KimEmail author
Nutrition Journal201716:7
DOI: 10.1186/s12937-017-0232-y
© The Author(s). 2017
Received: 27 October 2016
Accepted: 23 January 2017
Published: 31 January 2017
Abstract
Background
Although coffee consumption is
increasing rapidly, the results of previous studies regarding the
association between coffee consumption and stroke risk have been
conflicting. This was a multi-center cross-sectional study that aimed to
evaluate the relationship between coffee consumption and stroke risk in
Korean population.
Methods
Data were obtained from the
Health Examinees (HEXA) Study, which involved 146,830 individuals aged
40–69 years. Coffee consumption was categorized as none, < 1 cup/day,
1 to < 3 cups/day, and ≥ 3 cups/day. We used logistic regression
models to examine the association between coffee consumption and the
risk of stroke while controlling for potential confounders and performed
subgroup analyses.
Results
After adjusting for age and
various possible confounders, high coffee consumption was associated
with a 38% lower odds ratio for stroke in women (none vs. ≥ 3 cups/day:
OR, 0.62; 95% CI 0.47-0.81; P for trend < 0.0001). No significant association was found in men (none vs. ≥ 3 cups/day: OR, 0.84; 95% CI, 0.66-1.07; P
for trend = 0.1515). In analyses stratified by covariates, an inverse
association between coffee consumption and stroke risk was most evident
among healthy women who were younger, non-obese, non-hypertensive,
non-diabetic, non-smokers, and non-alcohol drinkers.
Conclusion
Our results suggest that
higher coffee consumption may have protective benefits with regards to
stroke risk in middle-aged Korean women.
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