Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 29,828 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke. DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain!trillions and trillions of neuronsthatDIEeach day because there areNOeffective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.
Monday, April 9, 2018
Stroke Recovery Drug Found Effective In Rewiring Brains Of Mice And Monkeys
Researchers in Japan have discovered that a
drug called edonerpic maleate has proven effective in aiding laboratory
mice and monkeys recover from strokes. The drug helps rewire the damaged
brain of stroke victims and aids in improving their recovery.
As reported by MedicalXpress this week, several institutions
in Japan conducted experiments to ascertain the possibility of
introducing a drug into the brain that would ally itself with a protein
called CRMP2-binding compound, which has been shown as involved in the
work of rewiring a damaged brain.
Edonerpic maleate was a drug that had shown just such promise in prior
research. Researchers found that the use of the drug in laboratory mice
just a day after suffering strokes helped improve the rewiring of the
damaged brains.
The
rewiring is important in that brain damage occurs in stroke victims
through a lack of oxygen (because of blood vessels being blocked or
bursting). The brain is then unable to repair the dead nerve cells.
Still, the brain is able to rewire itself somewhat — doing so in
unharmed parts of the brain — through physical therapy.
However, it was also found that only providing the mice with the drug
was not enough to improve the victims’ motor skills. That required
physical therapy in addition to the drug.
Follow-up tests were then conducted involving monkeys with strokes. The results were similar.
Edonerpic
maleate has already passed tests showing it safe for humans.
Researchers are now looking to conduct a clinical trial for the drug.
The research describing the study and its results has been published in the journal Science.
Daisy Daisy/Shutterstock
The new research adds to the growing methods by which stroke victims can be treated. Back in 2016, MedicalXpress
reported that researchers at the University of Manchester in England
discovered that an anti-inflammatory drug called interleukin-1 receptor
antagonist (IL-1Ra), already being used in treating humans with
rheumatoid arthritis and other conditions, reduced damage to brain cells
in mice when given early in a stroke’s aftermath. The research also
found that the number of new neurons increased, suggested new
generation, within the following days.
According to statistics compiled by the Centers for Disease Control and Prevention, 795,000 people in the United States suffer a stroke
each year. Of those, 140,000 die. Roughly 87 percent of all stroke
victims suffer what is known as ischemic stroke, the event that occurs
when the blood flow within the brain is blocked.
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