Gout may lessen Alzheimer risk
People who suffer from gout can take comfort in one thing: they may be less likely to develop Alzheimer's disease, researchers said Wednesday.
The
same uric acid that can crystallise to cause gout, a form of arthritis,
may protect against Alzheimer's, they wrote in the online journal
Annals of the Rheumatic Diseases.
Testing a theory that
antioxidant properties in uric acid may protect the brain, experts from
the United States and Canada looked at the records of 3.7 million people
over the age of 40 in a British database of medical charts.Researchers compared data on people with gout, and those without, who developed Alzheimer's disease in a followup period of about five years.
The researchers identified 309 new cases of Alzheimer's among 59,224 gout sufferers with an average age of 65, and 1,942 cases among 238,805 non-sufferers.
This amounted
to a 24 percent lower risk of Alzheimer's disease for people with a
history of gout, after factoring in differences in age, gender,
bodyweight, lifestyle and health.
"Our
findings provide the first population-based evidence for the potential
protective effect of gout on the risk of AD (Alzheimer's disease) and
support the purported neuroprotective role of uric acid," the authors
said in a statement.
Gout
happens when excess uric acid builds up in the blood, causing crystals
to form around the joints, inflicting extreme pain and swelling.
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