Deans' stroke musings: What does research reproducibility mean?

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, June 1, 2016

What does research reproducibility mean?

I'd be willing to bet that none of the clinical stroke research trials since forever are reproducible or replicable. Because they don't have an objective starting point of exact description of the size and location of the dead/damaged areas.
Definitions from Retraction Watch
Here’s how the US National Science Foundation (NSF) defines “reproducibility,” according to the authors:

…reproducibility refers to the ability of a researcher to duplicate the results of a prior study using the same materials as were used by the original investigator. That is, a second researcher might use the same raw data to build the same analysis files and implement the same statistical analysis in an attempt to yield the same results…. Reproducibility is a minimum necessary condition for a finding to be believable and informative.

And here’s how the NSF defines “replicability,” the authors say:

…the ability of a researcher to duplicate the results of a prior study if the same procedures are followed but new data are collected.

What does research reproducibility mean?

Steven N. Goodman*,
Daniele Fanelli and
John P. A. Ioannidis

+ Author Affiliations

↵*Corresponding author. Email: steve.goodman@stanford.edu

Science Translational Medicine 01 Jun 2016:
Vol. 8, Issue 341, pp. 341ps12
DOI: 10.1126/scitranslmed.aaf5027

You are currently viewing the abstract.
View Full Text

Abstract

The language and conceptual framework of “research reproducibility” are nonstandard and unsettled across the sciences. In this Perspective, we review an array of explicit and implicit definitions of reproducibility and related terminology, and discuss how to avoid potential misunderstandings when these terms are used as a surrogate for “truth.”