Deans' stroke musings: Cardiovascular effects of energy drinks in familial long QT syndrome: A randomized cross-over study

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, February 18, 2017

Cardiovascular effects of energy drinks in familial long QT syndrome: A randomized cross-over study

I'm sure your doctor has already told you if you have long QT syndrome, so you have no need to read up on your own. You will need to extrapolate if the energy drink consumption causes blood pressure spikes in you.
https://www.mdlinx.com/internal-medicine/medical-news-article/2017/02/14/lqts-long-qt-syndrome-qtc-corrected/7051598/?

International Journal of Cardiology, 02/14/2017

Gray B, et al. – This study suggests that caffeinated energy drinks markedly alter the cardiovascular dynamics in patients with long QT syndrome (LQTS). These drinks specifically trigger an acute increase in blood pressure. Moreover, these should be cautiously consumed by young patients considering their ability to trigger dangerous QTc prolongation in some LQTS patients.

Methods

From 2014–2016, 24 LQTS patients aged 16–50 years were recruited to a randomized, double-blind, cross-over study of energy drink (ED) versus control (CD) with participants acting as their own controls (one week washout).
The primary study outcome was an increase in corrected QT interval (QTc) by >20ms and, secondary outcomes were changes in systolic and diastolic blood pressure.

Results

Findings demonstrated that in 24 patients with LQTS (no dropout), mean age was 29 ± 9 years, 13/24 (54%) were female, and 8/24 (33%) were probands. Intention to treat analysis revealed no significant change in QTc with ED compared with CD (12 ± 28 ms vs 16 ± 27 ms, 3% vs 4%, p = 0.71).
Researchers observed that the systolic and diastolic blood pressure significantly increased with ED compared to CD (peak change 7 ± 16 mmHg vs 1 ± 16 mmHg, 6% vs 0.8%, p = 0.046 and 8 ± 10 vs 2 ± 9 mmHg, 11% vs 3% p = 0.01 respectively).
They found that these changes correlated with significant increases in serum caffeine (14.6 ± 11.3 vs 0.5 ± 0.1μmol/L, p < 0.001) and serum taurine (737 ± 199 vs -59 ± 22μmol/L, p < 0.001).
Also, data reported three patients with dangerous QTc prolongation of ≥50ms following energy drink consumption.

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