Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, May 19, 2022

Does Spasticity Reduction by Botulinum Toxin Type A Improve Upper Limb Functionality in Adult Post-Stroke Patients? A Systematic Review of Relevant Studies

 My botox shots did nothing to improve my arm use, because botox does nothing directly to fix the brain problem that causes spasticity.

Does Spasticity Reduction by Botulinum Toxin Type A Improve Upper Limb Functionality in Adult Post-Stroke Patients? A Systematic Review of Relevant Studies

2013, Journal of Neurology & Neurophysiology
 
 
Research ArticleOpen Access
Intiso et al., J Neurol Neurophysiol 2013, 4:4http://dx.doi.org/10.4172/2155-9562.1000167
 
Review ArticleOpen Access
Neurology & Neurophysiology
Volume 4 • Issue 4 • 1000167J Neurol NeurophysiolISSN: 2155-9562 JNN, an open access journal Stroke: Cerebrovascular Accident
Does Spasticity Reduction by Botulinum Toxin Type A Improve Upper Limb Functionality in Adult Post-Stroke Patients? A Systematic Review of Relevant Studies
Domenico Intiso
1
*, Valentina Simone
2
, Filomena Di Rienzo
1
, Andrea Santamato
3
, Mario Russo
1
, Maurizio Tolfa
1
, and Mario Basciani
1
1
Neuro-Rehabilitation Unit, Scientic Institute, Hospital ‘Casa Sollievo della Sofferenza’, Italy
2
Foundation rehabilitation “Gli Angeli di P.Pio”, San Giovanni Rotondo, Italy
3
Department of Physical Medicine and Rehabilitation, “OORR Hospital”, University of Foggia, Italy
*Corresponding author:
 Domenico Intiso MD, Neuro-Rehabilitation Unit, Hospital
Scientic Institute “Casa Sollievo della Sofferenza”, Viale dei Cappuccini, 71013 San Giovanni Rotondo (FG), Italy, Tel: 039 882 410 942; Fax: 039 882 410 942; E-mail: d.intiso@operapadrepio.it
,
 d.intiso@alice.it
Received
 
July 02, 2013;
Accepted
 October
 09, 2013;
Published
 October
 15
,
2013
Citation:
 Intiso D, Simone
V, Rienzo FD
, Santamato A, Russo
M, et al.
 
(2013) J Neurol
Neurophysiol 4: 167. doi:10.4172/2155-9562.1000167
Copyright:
 © 2013

Abstract

Objective
 
Botulinum toxin type A (BTX-A) use reduces upper limb (UL) spasticity in stroke patients, but the effects on functional recovery remain uncertain. The aim of present review was to ascertain if the reduction of spasticity by use of BTX-A was linked to a functional gain of UL or in activity of daily living in post-stroke patients.
Data source
: Search of relevant studies was conducted on MEDLINE, the Cochrane Central Register of Controlled Trials and EMBASE (1995 to July 2012).
Study selection
: Only randomized studies (RT) treating patients with UL post-stroke spasticity by BTX-A injection were included. Prospective open label, case series, cohort studies and case reports were excluded.
Data synthesis
: Thirty-four RTs were individuated, but only 16 were considered in the analysis. Trials varied widely in methodological design and measures used in assessing UL ability. Benet in UL functional recovery was reported in 13 studies, but only in six the result was signicant.
Conclusion
: some oriented-focused movements of UL unequivocally improve after reduced spasticity by BTX-A treatment, but evidence that arm functionality in adult post-stroke patients significantly benefit from this intervention is still doubt. No improvement in global functionality of activity daily living was observed.

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