Or is the actual stroke itself? Ask for proof as to the conclusion.
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5. long-term exposure to particulate matter speeded up cognitive decline in older women.
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11. Afib Linked to Cognitive Decline
And the new infection reason here;
http://www.neurology.org/content/80/13/1209.abstract
Abstract
Objective: We hypothesized that infectious burden (IB), a composite serologic measure of exposure to common pathogens (i.e., Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus, and herpes simplex virus 1 and 2) associated with vascular risk in the prospective Northern Manhattan Study
(NOMAS), would also be associated with cognition.
Methods: Cognition
was assessed using the Mini-Mental State Examination (MMSE) at
enrollment and the modified Telephone Interview
for Cognitive Status (TICS-m) at annual
follow-up visits. Adjusted linear and logistic regressions were used to
measure the
association between IB index and MMSE.
Generalized estimating equation models were used to evaluate
associations with TICS-m
and its change over time.
Results: Serologies
and cognitive assessments were available in 1,625 participants of the
NOMAS cohort. In unadjusted analyses, higher
IB index was associated with worse cognition
(change per standard deviation [SD] of IB for MMSE was −0.77, p < 0.0001, and for first measurements of TICS-m was −1.89, p < 0.0001). These effects were attenuated after adjusting for risk factors (for MMSE adjusted change per SD of IB = −0.17,
p = 0.06, for TICS-m adjusted change per SD IB = −0.68, p
< 0.0001). IB was associated with MMSE ≤24 (compared to MMSE >24,
adjusted odds ratio 1.26 per SD of IB, 95% confidence interval
1.06–1.51). IB was not associated with cognitive
decline over time. The results were similar when IB was limited to
viral
serologies only.
Conclusion: A measure of IB associated with stroke risk and atherosclerosis was independently associated with cognitive performance in
this multiethnic cohort. Past infections may contribute to cognitive impairment.
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