Deans' stroke musings: Corticospinal responses of quadriceps are abnormally coupled with hip adductors in chronic stroke survivors

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, May 17, 2013

Corticospinal responses of quadriceps are abnormally coupled with hip adductors in chronic stroke survivors

So ask your therapist what therapy protocol will correct that problem. You do expect them to know how to fix it, don't you? Sounds right up your alley Amy. And I know I'm being a bastard. I expect a lot from myself and even more from my medical team.
http://search.naric.com/research/rehab/redesign_record.cfm?search=2&type=all&criteria=J65578&phrase=no&rec=120874

NARIC Accession Number: J65578. What's this?
ISSN: 0014-4886.
Author(s): Krishnan, Chandramouli; Dhaher, Yasin.
Project Number: H133E070013.
Publication Year: 2012.
Number of Pages: 8.
Abstract: Study investigated whether the neural substrates mediating abnormal activation patterns after stroke are of cortical origin. Eight chronic stroke survivors, seven able-bodied young control subjects and four older adults participated in this research study. Data from older adults were used to evaluate whether aging contributes to abnormal coupling of the corticospinal responses. A novel transcranialmagnetic stimulation (TMS) protocol was developed to evaluate the extent of abnormal across-joint coupling of corticospinal responses in chronic stroke survivors. It was hypothesized that the stroke subjects would demonstrate abnormal higher corticospinal responses of the quadriceps muscle group during an isometric hip adduction task. TMS-elicited motor evoked potentials (MEPs) were recorded from the paretic leg of the stroke survivors and from the dominant leg of the control subjects using surface electromyography. Results indicated that, in stroke survivors, the magnitudes of MEPs of the vastus lateralis and vastus medialis during isometric hip adduction were significantly higher than those recorded during knee extension at similar background activity. Furthermore, MEP coupling ratios of the quadriceps muscles were significantly different than those observed in healthy controls. No significant differences in MEP coupling ratios were observed between the younger and older adults. These findings provide evidence for the first time that stroke subjects exhibit abnormal excitability of the quadricepsmuscle corticospinal neurons when performing isometric hip adduction. Importantly, the abnormal corticospinal responses observed in stroke subjects were not mediated by aging.