Deans' stroke musings: Abnormal white matter integrity in the corpus callosum among smokers: tract-based spatial statistics

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, June 9, 2014

Abnormal white matter integrity in the corpus callosum among smokers: tract-based spatial statistics

What I want to know and your doctor probably has to talk to the researchers. Is the problem because of nicotine or smoking? What was their smoking history? I plan on getting nicotine somehow after my next stroke for these reasons; Vaping sounds like a good option.
Nicotine and stroke rehab

The alarmist view here;
http://www.ncbi.nlm.nih.gov/pubmed/24516568

Umene-Nakano W¹, Yoshimura R¹, Kakeda S², Watanabe K², Hayashi K¹, Nishimura J², Takahashi H³, Moriya J², Ide S², Ueda I², Hori H¹, Ikenouchi-Sugita A¹, Katsuki A¹, Atake K¹, Abe O⁴, Korogi Y², Nakamura J¹.

Author information

Abstract

In the present study, we aimed to investigate the difference in white matter between smokers and nonsmokers. In addition, we examined relationships between white matter integrity and nicotine dependence parameters in smoking subjects. Nineteen male smokers were enrolled in this study. Eighteen age-matched non-smokers with no current or past psychiatric history were included as controls. Diffusion tensor imaging scans were performed, and the analysis was conducted using a tract-based special statistics approach. Compared with nonsmokers, smokers exhibited a significant decrease in fractional anisotropy (FA) throughout the whole corpus callosum. There were no significant differences in radial diffusivity or axial diffusivity between the two groups. There was a significant negative correlation between FA in the whole corpus callosum and the amount of tobacco use (cigarettes/day; R = - 0.580, p = 0.023). These results suggest that the corpus callosum may be one of the key areas influenced by chronic smoking.