Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, January 12, 2017

Our senses can’t learn under stress

You are under considerable stress since your doctor knows NOTHING about getting you to 100% recovery. Is that stress contributing to your lack of recovery? A very simple question for your doctor to answer, not dodge the question.
http://www.alphagalileo.org/ViewItem.aspx?ItemId=171513&CultureCode=en
Stress is part of our everyday lives – while some thrive on it, it makes others sick. But what does stress do to our senses?
When we train them, we can sharpen our senses thereby improve our perceptual performance. The stress hormone cortisol completely blocks this important ability. In the current issue of “Psychoneuroendocrinology” neuroscientists of the Ruhr University Bochum (RUB) report on this finding.
“Previous research has already shown that stress can prevent the retrieval of memories. But now we have discovered that it also has a major effect on our perception and perceptual learning,” explains Dr Hubert Dinse, one of the authors of the study.
Tactile sense in training
In their study, researchers investigated how the sense of touch of 30 study participants could be changed after a training phase. Half of them received a medium dose of the stress hormone cortisol, while the other half received a placebo drug.
To make training comparable across all participants, the researchers employed the well-established approach of passive finger stimulation. Previous studies and several therapy approaches have shown that this method leads to an improved tactile acuity.
Tactile performance was assessed using the so-called “two-point discrimination threshold”. This marker indicates how far apart two stimuli need to be, to be discriminated as two separate sensations – the closer they are, the better the sense of touch.
No learning effect after cortisol
The placebo group improved their tactile acuity, as expected, by about 15 percent. In contrast, the cortisol given to the other group blocked almost all the stimulation-induced improvement. Cognitive psychologist Prof Dr Oliver T. Wolf explains:” Our data show that a single dose of cortisol not only disrupts memory in the hippocampus, but it also has a substantial effect on the plasticity of sensory areas of the brain.”
Cortisol blocks synaptic connections
In previous studies on a cellular level, neuroscientists have demonstrated that cortisol suppresses the strengthening of synaptic connections, and therefore the plasticity of the brain – its ability to learn. The team led by Hubert Dinse therefore suggests, their results could also explain by cortisol-induced suppression of synaptic plasticity.
Effects on clinical treatments
The results of the study could also affect clinical treatments. Corticosteroids, of which cortisol is one, are often used in the treatment of immunological and neurological diseases. However, the effects on perceptual learning observed in this study may counteract rehabilitation efforts, which rely on just these mechanisms. It is therefore necessary to find out which effects the clinical treatment with these substances has on learning mechanisms in the brain.
Funding
Scientists from the fields of neuroinformatics and cognitive psychology, as well as from the Neurological Clinic Bergmannsheil collaborated on this research project. They were all funded by a grant to Collaborative Research Centre 874 from the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG).
http://news.rub.de/english/press-releases

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