Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, March 26, 2020

Recombinant Human Growth Hormone Ameliorates Cognitive Impairment in Stroke Patients

What is your doctor doing to recover your 5 lost cognitive years from your stroke? 

Did your doctor and stroke hospital do one damn thing with all this earlier research? I'd suggest mass firings.

Growth Hormone Improves Cognitive Function After Experimental Stroke

April 2018

Growth Hormone (GH) Administration Increases the Metabolic Activity of the left Hippocampus in an Elder Patient with Cognitive Disorders

May 2018

Growth hormone could play critical role in stroke rehabilitation and recovery, Hunter researchers say

 

May 2018

Brain fertiliser nurtures new hope for stroke survivors

September 2018

11 Ways to Boost Human Growth Hormone (HGH) Naturally

September 2018 

This is your doctor's responsibility, don't let her/him wash their hands of it and ignore the problem they caused by doing nothing to stop the 5 causes of the neuronal cascade of death in the first week. 

The latest here:

Recombinant Human Growth Hormone Ameliorates Cognitive Impairment in Stroke Patients



Abstract

Objective 
We aimed to determine the effects of recombinant human growth hormone (rhGH) replacement on cognitive function in subjects with poststroke cognitive impairment using resting-state functional magnetic resonance imaging. 
Methods 
We included 60 patients with a first-ever stroke for 3 months and a diagnosis of cognitive impairment who were randomized 1:1 to receive either rhGH subcutaneously or placebo injection for 6 months. All subjects were required to receive the same rehabilitative therapy program. Both groups were subjected to pretreatment and posttreatment neuropsychological assessment using the Montreal Cognitive Assessment, serum neurotrophic factors, biomarkers of glucose and lipid metabolism, and functional magnetic resonance imaging during 6 months of the study period. The pattern of brain activity was determined by examining the functional connectivity and amplitude of low-frequency fluctuations (ALFF) of blood oxygen level dependent signal. 
Results 
Forty-three (82.7%) completed the study. Treatment with rhGH reduced levels of triglycerides and low-density lipoprotein cholesterol but did not significantly altered plasma concentrations of glucose and glycated hemoglobin. We found a significant increase in serum insulin-like growth factor 1 levels (32.6%; P < 0.001) in the rhGH-treated group compared with that in the controls. After 6 months of rhGH treatment, mean Montreal Cognitive Assessment score improved from 16.31 (5.32) to 21.19 (6.54) (P < 0.001). The rhGH group showed significant increased area of activation with increased ALFF values in the regions of the frontal lobe, putamen, temporal lobe, and thalamus (P < 0.05), relative to the baseline conditions. The correlation analysis revealed that the ALFF and functional connectivity of default mode network was positively correlated with the ΔMoCA score and ΔIGF-1 levels; that is, the more the scale score increased, the higher the functional connection strength. No undesirable adverse effects were observed. 
Conclusions
The rhGH replacement has a significant impact on global and domain cognitive functions in poststroke cognitive impairment.


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