Deans' stroke musings: Identifiable patterns of trait, state, and experience in chronic stroke recovery

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, March 19, 2021

Identifiable patterns of trait, state, and experience in chronic stroke recovery

What the hell good does this do in getting survivors recovered?

Identifiable patterns of trait, state, and experience in chronic stroke recovery

Neurorehabilitation and Neural Repair (NNR) , Volume 35(2) , Pgs. 158-168.

NARIC Accession Number: J85576. What's this?
ISSN: 1545-9683.
Author(s): Duncan, E. Susan ; Shereen, A. Duke ; Gentimis, Thanos ; Small, Steven L..
Publication Year: 2021.
Number of Pages: 11.

Abstract:

Study investigated the stability of the brain’s functional connectivity across tasks and sessions in individuals with chronic stroke using a supervised machine learning approach. Twelve individuals with chronic stroke underwent functional magnetic resonance imaging (fMRI) seven times over 18 weeks. The middle 6 weeks consisted of intensive aphasia therapy. fMRI data were collected during rest and performance of 2 tasks. Functional connectivity metrics were calculated for each imaging run, then applied a support vector machine to classify data based on participant, task, and time point (pre- or posttherapy). Permutation testing established statistical significance. Whole-brain functional connectivity matrices could be classified at levels significantly greater than chance based on participant (87.1 percent accuracy), task (68.1 percent accuracy), and time point (72.1 percent accuracy). All significant effects were reproduced using only the contralesional right hemisphere; the left hemisphere revealed significant effects for participant and task, but not time point. Resting-state data could also be used to classify task-based data according to subject (66.0 percent). While the strongest posttherapy changes occurred among regions outside putative language networks, connections with traditional language-associated regions were significantly more positively correlated with behavioral outcome measures, and other regions had more negative correlations and intrahemispheric connections. The findings suggest the profound importance of considering interindividual variability when interpreting mechanisms of recovery in studies of functional connectivity in stroke.
Descriptor Terms: APHASIA, BRAIN, IMAGING, STROKE.

Can this document be ordered through NARIC's document delivery service*?: Y.

Citation: Duncan, E. Susan , Shereen, A. Duke , Gentimis, Thanos , Small, Steven L.. (2021). Identifiable patterns of trait, state, and experience in chronic stroke recovery. Neurorehabilitation and Neural Repair (NNR) , 35(2), Pgs. 158-168. Retrieved 3/19/2021, from REHABDATA database.

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More information about this publication:
Neurorehabilitation and Neural Repair (NNR).