Since we don't have a stroke organization in charge to update and run the stroke strategy this new idea will fall thru the cracks. You could talk to the ASA, NSA, WSO but that will be worthless.
http://www.alphagalileo.org/ViewItem.aspx?ItemId=150657&CultureCode=en
Materials resulting from chemical bonding of glucosamine, a type of
sugar, with fullerenes, kind of nanoparticles known as buckyballs, might
help to reduce cell damage and inflammation occurring after stroke. A
team from the Max Planck Institute in Germany has tested this on mice,
opening the door to potential new drugs for the cerebrovascular
accident.
The majority of stroke occurs when the blood vessels
that reach the brain are blocked by clots or fatty deposits which
decrease the flow of blood towards its cells. It is then that an
ischemic attack occurs, a pathology that leads to the degeneration of
neurones, which can be fatal and not many drugs can treat.
Now,
German and Swiss scientists have discovered that the combination of two
substances help to reduce inflammation and the brain volume affected
after a cerebrovascular accident. This is glucosamine, an amino sugar
commonly used to treat arthritis and arthrosis; and certain derivatives
of fullerenes, hollow and spherical structures formed by many carbon
atoms.
Before now it was known that the fullerenes capture
chemical radicals well which makes them act as neuroprotective agents,
while the glucosamine brings down the inflammation.
What the
researchers have done is chemically bond the two compounds to produce
what is known as 'glyconanoparticles'. These have subsequently been
administered to laboratory rats which then had a cerebrovascular
accident induced.
The results, published in the journal
'Experimental Neurology', conclude that this combination of fullerene
derivatives and glucosamine reduces cell damage and inflammation after a
stroke, according to the MRI scans of animal brains and the improvement
of their neurological symptoms.
"Our study confirms that it is
possible to couple fullerenes with sugars in order to combine their
protective effects and in this way, to obtain new materials which may
help to prevent and to treat Stroke," says Guillermo Orts-Gil, a Spanish
researcher at the Max-Planck Institute of Colloids and Interfaces
(Germany) and co-author of the research.
"Although the present
study was carried out on mice, the results indicate that these sweet
buckyballs are potential new drugs for treating Stroke also in humans.
However, this must be taken with caution, since what works in mice does
not necessarily will work in the same way in humans," declared Orts-Gil.
This
work is the continuation of another previous piece of research,
published last year in the journal 'Nano Letters', in which the
researchers also confirmed that a protein called E-selectin, linked to
the chain of events that occur during a stroke, is distributed
throughout the brain and not only in the area where the stroke
originates, as previously thought.
Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 28,987 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
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