Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, March 13, 2015

Sweet nanoparticles target stroke

Since we don't have a stroke organization in charge to update and run the stroke strategy this new idea will fall thru the cracks.   You could talk to the ASA, NSA, WSO but that will be worthless.
http://www.alphagalileo.org/ViewItem.aspx?ItemId=150657&CultureCode=en
Materials resulting from chemical bonding of glucosamine, a type of sugar, with fullerenes, kind of nanoparticles known as buckyballs, might help to reduce cell damage and inflammation occurring after stroke. A team from the Max Planck Institute in Germany has tested this on mice, opening the door to potential new drugs for the cerebrovascular accident.

The majority of stroke occurs when the blood vessels that reach the brain are blocked by clots or fatty deposits which decrease the flow of blood towards its cells. It is then that an ischemic attack occurs, a pathology that leads to the degeneration of neurones, which can be fatal and not many drugs can treat.

Now, German and Swiss scientists have discovered that the combination of two substances help to reduce inflammation and the brain volume affected after a cerebrovascular accident. This is glucosamine, an amino sugar commonly used to treat arthritis and arthrosis; and certain derivatives of fullerenes, hollow and spherical structures formed by many carbon atoms.

Before now it was known that the fullerenes capture chemical radicals well which makes them act as neuroprotective agents, while the glucosamine brings down the inflammation.

What the researchers have done is chemically bond the two compounds to produce what is known as 'glyconanoparticles'. These have subsequently been administered to laboratory rats which then had a cerebrovascular accident induced.

The results, published in the journal 'Experimental Neurology', conclude that this combination of fullerene derivatives and glucosamine reduces cell damage and inflammation after a stroke, according to the MRI scans of animal brains and the improvement of their neurological symptoms.

"Our study confirms that it is possible to couple fullerenes with sugars in order to combine their protective effects and in this way, to obtain new materials which may help to prevent and to treat Stroke," says Guillermo Orts-Gil, a Spanish researcher at the Max-Planck Institute of Colloids and Interfaces (Germany) and co-author of the research.

"Although the present study was carried out on mice, the results indicate that these sweet buckyballs are potential new drugs for treating Stroke also in humans. However, this must be taken with caution, since what works in mice does not necessarily will work in the same way in humans," declared Orts-Gil.

This work is the continuation of another previous piece of research, published last year in the journal 'Nano Letters', in which the researchers also confirmed that a protein called E-selectin, linked to the chain of events that occur during a stroke, is distributed throughout the brain and not only in the area where the stroke originates, as previously thought.

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