Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:

Tuesday, December 6, 2016

Effects of pomegranate juice on blood pressure: A systematic review and meta-analysis of randomized controlled trials

What the fuck will it take to write up a protocol on this? This earlier research wasn't good enough so you had to repeat it? No mention of amounts so this was totally useless. God, the stupidity and waste of resources.

Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation  Aug. 2008

 And this one from 2006:

Regular pomegranate juice administered to hypertensive patients caused a significant drop in blood pressure [26], a reduction in carotid plaque development [27]  Aug. 2006 

And the latest here:

Effects of pomegranate juice on blood pressure: A systematic review and meta-analysis of randomized controlled trials

In this study, researchers systematically review and meta–analyze accessible proof from randomized placebo–controlled trials (RCTs) researching the impacts of pomegranate juice intake and blood pressure (BP). The present meta–analysis recommends consistent benefits of pomegranate juice intake on BP. This evidence recommends it might be prudent to include this fruit juice in a heart–healthy diet.
  • A comprehensive literature look in Medline and Scopus was completed to distinguish qualified RCTs.
  • A meta–analysis of qualified reviews was performed utilizing a random–effects model.
  • Quality assessment, sensitivity analysisand publication bias assessments were led utilizing standard methods.
  • Quantitative information synthesis from 8 RCTs indicated significant decreases in both systolic [weighed mean difference (WMD): –4.96 mmHg, 95% CI: –7.67 to –2.25, p < 0.001) and diastolic BP (WMD: –2.01 mmHg, 95% CI: –3.71 to –0.31, p = 0.021) after pomegranate juice intake.
  • Consequences for SBP stayed stable to sensitivity investigations.
  • Pomegranate juice diminished SBP regardless of the duration (>12 wks: WMD = –4.36 mmHg, 95% CI: –7.89 to –0.82, p = 0.016) and <12 wks: WMD = –5.83 mmHg, 95% CI: –10.05 to –1.61, p = 0.007) and dose consumed (>240 cc: WMD = -3.62 mmHg, 95% CI: –6.62 to –0.63, p = 0.018) and <240 cc: WMD = –11.01 mmHg, 95% CI: –17.38 to –4.65, p = 0.001, pomegranate juice per day) whereas doses >240 cc provided a borderline significant impact in lessening DBP.
Go to PubMed Go to Abstract Print Article Summary Cat 2 CME Report

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