Deans' stroke musings: Prestroke vascular pathology and the risk of recurrent stroke and poststroke dementia

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, January 19, 2017

Prestroke vascular pathology and the risk of recurrent stroke and poststroke dementia

Your doctor can tell you exactly what this 2-fold increase in dementia risk means compared to these other research results.

1. A documented 33% dementia chance post-stroke from an Australian study? May 2012.

2. Then this study came out and seems to have a range from 17-66%. December 2013.

3. A 20% chance in this research. July 2013.

https://www.mdlinx.com/neurology/medical-news-article/2016/08/08/dementia-epidemiology-prognosis-risk-factors-stroke/6769824/
Stroke, 08/08/2016
Portegies MLP, et al.

The physicians determined the long–term risk of recurrent stroke and dementia, and the proportion of recurrent strokes and poststroke dementia cases that are attributable to prestroke cardiovascular risk factors (ie, the population attributable risk), within the population–based Rotterdam Study. The study reveal that long–term risks of recurrent stroke and poststroke dementia remain high and are significantly influenced by prestroke risk factors, emphasizing the requirement for optimizing primary prevention.

Methods

For this study, 1237 patients were followed up with 1^st-ever stroke and 4928 stroke-free participants, matched on age, sex, examination round, and stroke date (index date), for the occurrence of stroke or dementia.
In both groups incidence rates were calculated and estimated the individual and combined population attributable risk of prestroke cardiovascular risk factors for both outcomes.

Results

Patients retained a 3-fold increased risk of recurrent stroke and an almost 2-fold increased risk of dementia compared with people without stroke, beyond 1 year after stroke.
As per this study, 39% (95% confidence interval, 18%–66%) of recurrent strokes and 10% (95% confidence interval, 0%–91%) of poststroke dementia cases were attributable to prestroke cardiovascular risk factors.
The study reveal that these percentages were similar for 1^st-ever stroke and dementia in the matched stroke-free population.

Go to PubMed Go to Abstract Print Article Summary Cat 2 CME Report