Deans' stroke musings: Tomato and lycopene supplementation and cardiovascular risk factors: A systematic review and meta-analysis

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, January 19, 2017

Tomato and lycopene supplementation and cardiovascular risk factors: A systematic review and meta-analysis

What a waste. We have known for years that lycopene and tomatoes are good for you. What we need is amounts per body weights to keep some amount of lycopene circulating in the bloodstream. Have you no previous experience reading research and determining the next steps? The stupid - it burns.

Lycopene in tomatoes reduces stroke risk by more than 50% July 2013

Tomato Pill’ Improves Blood Vessel Function June 2014

Health effects of lycopene, a carotenoid found mainly from tomato products Aug. 2016

Serum lycopene decreases the risk of stroke in men: A population-based follow-up study. Oct. 2012

https://www.mdlinx.com/internal-medicine/medical-news-article/2017/01/19/tomato-lycopene-intervention-cardiovascular-risk-factors/7012407/?

Atherosclerosis, 01/19/2017

Cheng HM, et al. – This study suggests a positive influence of tomato products and lycopene supplementation on blood lipids, blood pressure and endothelial function. These outcomes support the development of promising individualised nutritional strategies involving tomatoes to tackle cardiovascular diseases (CVD).

Methods

Researchers searched 3 databases including Medline, Web of science, and Scopus from inception to August 2016.
Inclusion criteria were: intervention randomised controlled trials reporting effects of tomato products and lycopene supplementation on CV risk factors among adult subjects >18 years of age.
The outcomes of interest included blood lipids (total-, HDL-, LDL-cholesterol, triglycerides, oxidised-LDL), endothelial function (flow-mediated dilation (FMD), pulse wave velocity (PWV)) and blood pressure (BP) inflammatory factors (CRP, IL-6) and adhesion molecules (ICAM-1).
They used random-effects models to determine the pooled effect sizes.

Results

Data showed that out of 1189 publications identified, 21 fulfilled inclusion criteria and were meta-analysed.
Overall, findings demonstrated that interventions supplementing tomato were associated with significant reductions in LDL-cholesterol (-0.22 mmol/L; p = 0.006), IL-6 (standardised mean difference -0.25; p = 0.03), and improvements in FMD (2.53%; p = 0.01); while lycopene supplementation reduced Systolic-BP (-5.66 mmHg; p = 0.002).
Additionally, it was noted that no other outcome was significantly affected by these interventions.

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