http://jneuroengrehab.biomedcentral.com/articles/10.1186/s12984-016-0204-z
- Ana Lúcia Faria†Email authorView ORCID ID profile,
- Andreia Andrade†,
- Luísa Soares and
- Sergi Bermúdez i Badia
†Contributed equally
Journal of NeuroEngineering and Rehabilitation201613:96
DOI: 10.1186/s12984-016-0204-z
© The Author(s). 2016
Received: 4 November 2015
Accepted: 25 October 2016
Published: 2 November 2016
Abstract
Background
Stroke is one of the most
common causes of acquired disability, leaving numerous adults with
cognitive and motor impairments, and affecting patients’ capability to
live independently. There is substancial evidence on post-stroke
cognitive rehabilitation benefits, but its implementation is generally
limited by the use of paper-and-pencil methods, insufficient
personalization, and suboptimal intensity. Virtual reality tools have
shown potential for improving cognitive rehabilitation by supporting
carefully personalized, ecologically valid tasks through accessible
technologies. Notwithstanding important progress in VR-based cognitive
rehabilitation systems, specially with Activities of Daily Living
(ADL’s) simulations, there is still a need of more clinical trials for
its validation. In this work we present a one-month randomized
controlled trial with 18 stroke in and outpatients from two
rehabilitation units: 9 performing a VR-based intervention and 9
performing conventional rehabilitation.
Methods
The VR-based intervention
involved a virtual simulation of a city – Reh@City - where memory,
attention, visuo-spatial abilities and executive functions tasks are
integrated in the performance of several daily routines. The
intervention had levels of difficulty progression through a method of
fading cues. There was a pre and post-intervention assessment in both
groups with the Addenbrooke Cognitive Examination (primary outcome) and
the Trail Making Test A and B, Picture Arrangement from WAIS III and
Stroke Impact Scale 3.0 (secondary outcomes).
Results
A within groups analysis
revealed significant improvements in global cognitive functioning,
attention, memory, visuo-spatial abilities, executive functions, emotion
and overall recovery in the VR group. The control group only improved
in self-reported memory and social participation. A between groups
analysis, showed significantly greater improvements in global cognitive
functioning, attention and executive functions when comparing VR to
conventional therapy.
Conclusions
Our results suggest that
cognitive rehabilitation through the Reh@City, an ecologically valid VR
system for the training of ADL’s, has more impact than conventional
methods.
Trial registration
This trial was not registered
because it is a small sample study that evaluates the clinical validity
of a prototype virtual reality system.
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