Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 29,132 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain!trillions and trillions of neuronsthatDIEeach day because there areNOeffective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.
Monday, November 6, 2017
Neurotrophins and Proneurotrophins: Focus on Synaptic Activity and Plasticity in the Brain
Neurotrophins
have been intensively studied and have multiple roles in the brain.
Neurotrophins are first synthetized as proneurotrophins and then cleaved
intracellularly and extracellularly. Increasing evidences demonstrate
that proneurotrophins and mature neurotrophins exerts opposing role in
the central nervous system. In the present review, we explore the role
of nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF),
neurotrophin 3 (NT3), and neurotrophin 4 (NT4) and their respective
proform in cellular processes related to learning and memory. We focused
on their roles in synaptic activity and plasticity in the brain with an
emphasis on long-term potentiation, long-term depression, and basal
synaptic transmission in the hippocampus and the temporal lobe area. We
also discuss new findings on the role of the Val66Met polymorphism on
the BDNF propeptide on synaptic activity.
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