Deans' stroke musings: May Growth Hormone be Useful for Regenerative Therapies With Stem Cells

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, January 23, 2018

May Growth Hormone be Useful for Regenerative Therapies With Stem Cells

Yes, once again followup is needed.

May Growth Hormone be Useful for Regenerative Therapies With Stem Cells

ABSTRACT

This study was designed for analyzing the current concepts about GH and stem cells treatments in some acquired neurological injuries(cerebral palsy, stroke, traumatic brain injury) and myocardial infarction. From this analysis we can conclude that while it seems that GH
plays an important therapeutic role, it is also clear that stem cells are a promising therapeutic alternative; although there is still a need to clarify what is the optimal window of time for their administration after each one of these damages, as well as the best route of administration in each case and the most appropriate number of stem cells that should be administered. Since the largest number of implanted stem cells do not integrate into the damaged tissue, but rather exert their actions by releasing a number of trophic factors, most of them physiologically induced by GH, and die within a few days after being administered, studies must be done to try to genetically modify these stem cells in GMP facilities so that they can replace and repair the damaged tissues. Here we also provide evidences indicating that GH administration may be of utility for increasing the number of endogenous, and exogenously administered, stem cells allowing their survival, differentiation and migration to the damaged area. In adition, we suggest that each individual may have their stem cells stored in a cell bank, so that he could receive them early after any of these injuries.
Keywords: Growth hormone, Stem cells, Cerebral palsy, Stroke, Traumatic brain injury, Cardiac infarction