http://www.crainscleveland.com/article/20180409/news/157666/cleveland-clinic-researchers-receive-25-million-stroke-research
A
team of researchers at Cleveland Clinic has been awarded a $2.5 million
grant to advance work using deep brain stimulation to improve
post-stroke motor rehabilitation, according to a news release.
Dr. Andre Machado and Ken Baker are co-primary investigators on the grant, which comes from the National Institutes of Health.
The grant will operate in parallel with their ongoing clinical trial that explores the use of deep brain stimulation to restore motor function in patients who have suffered a stroke.
"If this research succeeds, it offers new hope for patients who have suffered a stroke and have remained paralyzed," Machado, chair of the Cleveland Clinic Neurological Institute, said in a prepared statement. "It is an opportunity to allow our patients to rehabilitate and gain function and therefore gain independence."
The researcher team hopes to learn how the type of stroke influences the treatment's benefits. Understanding these dynamics better could help identify biomarkers that indicate which patients are good candidates for deep brain stimulation and may most benefit from the therapy, according to the release. The researchers also hope to learn how the timing of treatment onset and age may influence outcomes.
"This award will help us further refine our work in using cerebellar stimulation — DBS — to enhance motor rehabilitation," Baker, of the Cleveland Clinic Lerner Research Institute, said in a prepared statement. "There currently are no effective therapeutic treatments for the hundreds of thousands of individuals who live with chronic motor disabilities following stroke. We are hopeful this will reduce the burden of stroke on patients, their families and society."
Dr. Andre Machado and Ken Baker are co-primary investigators on the grant, which comes from the National Institutes of Health.
The grant will operate in parallel with their ongoing clinical trial that explores the use of deep brain stimulation to restore motor function in patients who have suffered a stroke.
"If this research succeeds, it offers new hope for patients who have suffered a stroke and have remained paralyzed," Machado, chair of the Cleveland Clinic Neurological Institute, said in a prepared statement. "It is an opportunity to allow our patients to rehabilitate and gain function and therefore gain independence."
The researcher team hopes to learn how the type of stroke influences the treatment's benefits. Understanding these dynamics better could help identify biomarkers that indicate which patients are good candidates for deep brain stimulation and may most benefit from the therapy, according to the release. The researchers also hope to learn how the timing of treatment onset and age may influence outcomes.
"This award will help us further refine our work in using cerebellar stimulation — DBS — to enhance motor rehabilitation," Baker, of the Cleveland Clinic Lerner Research Institute, said in a prepared statement. "There currently are no effective therapeutic treatments for the hundreds of thousands of individuals who live with chronic motor disabilities following stroke. We are hopeful this will reduce the burden of stroke on patients, their families and society."
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