If you really want to figure out how neuroplasticity works, this won't do it. You have to determine what the signals are that cause a neuron to give up its' current job and take on a neighboring neurons job. And you can do that by some of these methods:
1. Scientists Create Injectable Swarm of Brain Reading Nanosensors
2. Use
nanowires to listen in on single neurons
3. Or lay a grid across the cortex
to listen in.
Until we learn that exact mechanism, neuroplasticity will never be repeatable on demand.
Assessing the mechanisms of brain plasticity by transcranial magnetic stimulation
Neuropsychopharmacology (2022)
Abstract
Transcranial magnetic stimulation (TMS) is a non-invasive technique for focal brain stimulation based on electromagnetic induction where a fluctuating magnetic field induces a small intracranial electric current in the brain. For more than 35 years, TMS has shown promise in the diagnosis and treatment of neurological and psychiatric disorders in adults. In this review, we provide a brief introduction to the TMS technique with a focus on repetitive TMS (rTMS) protocols, particularly theta-burst stimulation (TBS), and relevant rTMS-derived metrics of brain plasticity. We then discuss the TMS-EEG technique, the use of neuronavigation in TMS, the neural substrate of TBS measures of plasticity, the inter- and intraindividual variability of those measures, effects of age and genetic factors on TBS aftereffects, and then summarize alterations of TMS-TBS measures of plasticity in major neurological and psychiatric disorders including autism spectrum disorder, schizophrenia, depression, traumatic brain injury, Alzheimer’s disease, and diabetes. Finally, we discuss the translational studies of TMS-TBS measures of plasticity and their therapeutic implications.
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