Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, March 14, 2023

Mozart music stimulation effect on wistar rats’ neurogenesis

Since BDNF  is good for our stroke rehabilitation, WHOM is going to do the human testing on this to see if it helps stroke recovery? With NO stroke leadership, NOTHING EVER OCCURS! Don't do this on your own until proven by research, you know how dangerous non-approved research is. 

 Mozart music stimulation effect on wistar rats’ neurogenesis

Anak Agung Ngurah Krisna Putra1, Irwanto1*, Reny I’tishom2,
Bagus Setyoboedi1, Muhammad R. D. Mustakim1
 
Introduction:  
 
Optimal brain development is required to achieve optimal health. Therefore, stimulation is needed to achieve optimal development, and one of the stimulations which can be provided is music stimulation. Several prior investigations have been completed to prove the impact of music stimulation on brain development, whose results still showed both pros
and cons. This investigation had the intention of determining musical stimulation’s impacts on neurogenesis.
 
Method:  
 
Thirty 30 days old male Wistar rats were grouped randomly but equally into experimental and control groups, with 15 rats in each group. The experimental group was exposed for 90 minutes twice a day in 30 constitutive days to Mozart music (Mozart Sonata for two pianos K. 448) with sound pressure levels between 60 and 80 dB. After 30 days, the rats were euthanized. The neurogenesis parameters, such as plasma corticosterone level, Brain-Derived Neurotrophic Factor (BDNF) and Insulin-like Growth Factor 1 (IGF-1) concentration, and cerebral cortex thickness, were assessed.
 
Result: 
 
 Rats with Mozart music exposure had considerably lower plasma corticosterone. They had substantially higher BDNF concentration in the hippocampus compared to the control group (p-value 0.049 and 0.040, respectively). Still, no significant effect was found on IGF-1 concentration and cerebral cortex thickness (p-value 0.148 and 0.094, respectively).
 
Conclusion: 
 
 The brain development process requires stimulation, and Mozart’s music is proven to be an alternative to stimulations provided for brain development.
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