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Progress in application of adult endogenous neurogenesis in brain injury repair
Author information
Sheng li xue bao : [Acta Physiologica Sinica],
01 Apr 2023, 75(2):231-240Language:chi
PMID: 37089097
Review
Abstract
Persistent
neurogenesis exists in the subventricular zone (SVZ) of the ventricles
and the subgranular zone (SGZ) of the dentate gyrus of the hippocampus
in the adult mammalian brain. Adult endogenous neurogenesis not only
plays an important role in the normal brain function, but also has
important significance in the repair and treatment of brain injury or
brain diseases. This article reviews the process of adult endogenous
neurogenesis and its application in the repair of traumatic brain injury
(TBI) or ischemic stroke, and discusses the strategies of activating
adult endogenous neurogenesis to repair brain injury and its practical
significance in promoting functional recovery after brain injury.
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