http://casereports.bmj.com/content/2013/bcr-2012-007455.abstract
Summary
A patient with a history of
deep vein thrombosis presented with painful bruising and blistering on
his left leg 7–10 days
after warfarin treatment. A complicated
2-month treatment followed, where vasculitis was originally diagnosed
from histological
findings before the final diagnosis of
warfarin-induced skin necrosis (WISN) was made on clinical grounds.
Warfarin was stopped,
reversed and low molecular weight
heparin started but, the lesions had progressed to full thickness
necrosis. This was originally
treated with conventional surgical
debridement before introducing maggot debridement therapy (MDT) in an
effort to try to
salvage the limb.
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