http://www.jneuroengrehab.com/content/11/1/160/abstract
Journal of NeuroEngineering and Rehabilitation 2014, 11:160
doi:10.1186/1743-0003-11-160
Published: 5 December 2014
Published: 5 December 2014
Abstract (provisional)
Background
A reduction of hemispatial neglect due to stroke has been associated with activation
of the contralesional hand in the contralesional hemispace. Robot-assisted upper limb
training was found to effectively improve paretic arm function in stroke patients.
To date no proof of concept of robot-assisted hemispatial neglect therapy has been
reported in literature. This study aimed to determine whether robot-assisted left
(contralesional) hand activation alone could lead to an improvement in hemispatial
neglect following stroke.
Methods
Three stroke patients with right brain injury underwent a 2-week training program
of robotic left hand activation with the Gloreha(R) hand rehabilitation glove, which
provides repetitive, passive mobilization of the fingers. Outcomes were assessed using
the Line Crossing test, the Bells test, the Sentence Reading test, the Saccadic Training,
the Sustained Attention to Response Task, and the Purdue Pegboard test.
Results
Changes were observed after treatment as follows. Line Crossing test: all patients
showed improved performance (6.7%, 89.5% and 80% increase in lines crossed) with two
patients reaching normal performance levels. Bells test: one patient improved performance
(50% increase), while one patient showed no change and one patient declined (-10.3%
change); no patient reached normal performance levels. Sentence Reading test: all
patients showed improved performance (800%, 57.1% and 42.9% increase in number of
sentences read) with no patient reaching normal performance level. Saccadic Training:
all patients showed improved performance (-62.8%, -15.5% and -9.7% change of the left
hemifield reaction time). Sustained Attention to Response Task: all patients showed
improved performance (-20.5%, -5.8% and -10% change of the reaction time) with two
patients reducing incorrect responses (-42.9% and -73.3%) and one patient increasing
them (9.1%). Purdue Pegboard test: all patients showed improved performance (100%,
27.3% and 75% change in the left + right + both hands sub-item score).
Conclusions
Some caution is warranted when interpreting our results, as the responses to the intervention
were variable and might have been due to a placebo effect or fluctuating clinical
conditions. However, robot-assisted hemispatial neglect therapy might be useful in
stroke patients. Larger-scale investigations are needed to confirm our preliminary
findings.
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